Jennifer Curtis

Jennifer Curtis

Jennifer Curtis

Professor, School of Physics

The Curtis lab is primarily focused on the physics of cell-cell and cell-extracellular matrix interactions, in particular within the context of glycobiology and immunobiology. Our newest projects focus on questions of collective and single cell migration in vitro and in vivo; immunophage therapy "an immunoengineering approach - that uses combined defense of immune cells plus viruses (phage) to overcome bacterial infections"; and the study of the molecular biophysics and biomaterials applications of the incredible enzyme, hyaluronan synthase. A few common scientific themes emerge frequently in our projects: biophysics at interfaces, the use of quantitative modeling, collective interactions of cells and/or molecules, cell mechanics, cell motility and adhesion, and in many cases, the role of bulky sugars in facilitating cell integration and rearrangements in tissues.

jcurtis6@gatech.edu

404.894.8839

Office Location:
MoSE G024/G128

Cell Physics Laboratory

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    University, College, and School/Department
    Research Focus Areas:
    • Biobased Materials
    • Biomaterials
    • Molecular, Cellular and Tissue Biomechanics
    Additional Research:

    Advanced characterization, cell biophysics, soft materials, tissue engineering, cell biophysics, cell mechanics of adhesion, migration and dynamics, immunophysics, immunoengineering, hyaluronan glycobiology, hyaluronan synthase, physics of tissues


    IRI Connections:

    Sam Brown

    Sam Brown

    Sam Brown

    Professor

    Sam Brown's lab studies the multi-scale dynamics of infectious disease. Their goal is to improve the treatment and control of infectious diseases through a multi-scale understanding of microbial interactions. Their approach is highly interdisciplinary, combining theory and experiment, evolution, ecology and molecular microbiology in order to understand and control the multi-scale dynamics of bacteria pathogens.

    sam.brown@biology.gatech.edu

    Office Location:
    ES&T 2244

    Website

  • http://biosci.gatech.edu/people/sam-brown
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    Research Focus Areas:
    • Drug Design, Development and Delivery
    • Molecular Evolution
    • Systems Biology
    Additional Research:
    Evolutionary microbiology, bacterial social life, virulence and drug resistance

    IRI Connections:

    Blair Brettmann

    Blair Brettmann

    Blair Brettmann

    Assistant Professor, School of Chemical and Biomolecular Engineering and Material Science and Engineering
    RBI Co-Lead: Interface of polymer science and wood-based materials

    Blair Brettmann received her B.S. in chemical engineering at the University of Texas at Austin in 2007. She received her Master’s in chemical engineering practice from MIT in 2009 following internships at GlaxoSmithKline (Upper Merion, PA) and Mawana Sugar Works (Mawana, India). Blair received her Ph.D. in chemical engineering at MIT in 2012 working with the Novartis-MIT Center for Continuous Manufacturing under Professor Bernhardt Trout. Her research focused on solid-state characterization and application of pharmaceutical formulations prepared by electrospinning. Following her Ph.D., Brettmann worked as a research engineer for Saint-Gobain Ceramics and Plastics for two years. While at Saint-Gobain she worked on polymer-based wet coatings and dispersions for various applications, including window films, glass fiber mats and architectural fabrics. Later, Brettmann served as a postdoctoral researcher in the Institute for Molecular Engineering at the University of Chicago with Professor Matthew Tirrell. Currently, Brettmann is an assistant professor with joint appointments in chemical and biomolecular engineering and Materials Science and Engineering at Georgia Tech.

    blair.brettmann@mse.gatech.edu

    404.894.2535

    Office Location:
    MoSE 31100P

    Website

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    Research Focus Areas:
    • Biobased Materials
    • Biochemicals
    • Biomaterials
    • Biorefining
    • Biotechnology
    • Drug Design, Development and Delivery
    • Pulp Paper Packaging & Tissue
    • Sustainable Manufacturing
    Additional Research:

    Pharmaceuticals, polymer and fiber, printing technologies, polymers, nanocellulose applications, new materials, wet-end chemistry, manufacturing, biotechnology, cellulosic nanomaterials, chemistry, biomaterials, aerogels and hydrogels, coating, coatings and barriers, films and coatings


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    Edward Botchwey

    Edward Botchwey

    Edward Botchwey

    Professor, Wallace H. Coulter Department of Biomedical Engineering

    Edward Botchwey received a B.S. in mathematics from the University of Maryland at College Park in 1993 and both M.E. and Ph.D. degrees in materials science engineering and bioengineering from the University of Pennsylvania in 1998 and 2002 respectively. He was recruited to the faculty at Georgia Tech in 2012 from his previous position at the University of Virginia. His current position is associate professor in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University. Botchwey is former Ph.D. fellow of the National GEM Consortium, a former postdoctoral fellow of the UNCF-Merk Science Initiative, and a recipient of the Presidential Early Career Awards for Scientists and Engineers from the National Institutes of Health. 

    Botchwey’s research focuses on the delivery of naturally occurring small molecules and synthetic derivatives for applications in tissue engineering and regenerative medicine. He is particularly interested in how transient control of immune response using bioactive lipids can be exploited to control trafficking of stem cells, enhance tissue vascularization, and resolve inflammation. Botchwey serves on the Board of Directors of the Biomedical Engineering Society (BMES) and serves as the secretary to the Biomedical Engineering Decade committee.

    Botchwey, his wife Nisha Botchwey (also a GT faculty member) and three children reside in east Atlanta in the Lake Claire neighborhood. Botchwey is also an avid cyclist and enjoys reading YA fantasy, behavioral neuroscience and Christian theology books in his personal time.

    edward.botchwey@bme.gatech.edu

    404.385.5058

    Website

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    Research Focus Areas:
    • Biobased Materials
    • Biomaterials
    • Chemical Biology
    • Regenerative Medicine
    Additional Research:

    Biomaterials, cellular materials, in situ characterization, tissue engineering, tissue engineering and biomaterials, microvascular growth and remodeling, stem cell engineering.


    IRI Connections:

    Andreas Bommarius

    Andreas Bommarius

    Andreas Bommarius

    Professor
    RBI Initiative Lead: A Renewables-based Economy from WOOD (ReWOOD)

    Andreas (Andy) S. Bommarius is a professor of Chemical and Biomolecular Engineering as well of Chemistry and Biochemistry at the Georgia Institute of Technology in Atlanta, GA.  He received his diploma in Chemistry in 1984 at the Technical University of Munich, Germany and his Chemical Engineering B.S. and Ph.D. degrees in 1982 and 1989 at MIT, Cambridge, MA.

    From 1990-2000, he led the Laboratory of Enzyme Catalysis at Degussa (now Evonik) in Wolfgang, Germany, where his work ranged from immobilizing homogenous catalysts in membrane reactors to large-scale cofactor-regenerated redox reactions to pharma intermediates.

    At Georgia Tech since 2000, his research interests cover green chemistry and biomolecular engineering, specifically biocatalyst development and protein stability studies.  His lab applies data-driven protein engineering to improve protein properties on catalysts ranging from ene and nitro reductases to cellobiohydrolases.  Bommarius has guided the repositioning of the curriculum towards Chemical and Biomolecular Engineering by developing new courses in Process Design, Biocatalysis and Metabolic Engineering, as well as Drug Design, Development, and Delivery (D4), an interdisciplinary course with Mark Prausnitz.

    Andy Bommarius in 2008 became a Fellow of the American Institute of Medical and Biological Engineering.  Since 2010, he is Director of the NSF-I/UCR Center for Pharmaceutical Development (CPD), a Center focusing on process development, drug substance and product stability, and novel analytical methods for the characterization of drug substances and excipients.

    andreas.bommarius@chbe.gatech.edu

    404-385-1334

    Office Location:
    EBB 5018

    Website

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    Research Focus Areas:
    • Biobased Materials
    • Biochemicals
    • Biorefining
    • Biotechnology
    • Drug Design, Development and Delivery
    • Molecular Evolution
    • Pulp Paper Packaging & Tissue
    • Renewable Energy
    • Sustainable Manufacturing
    Additional Research:
    Biomolecular engineering, especially biocatalysis, biotransformations, and biocatalyst stability. Biofuels. Enzymatic Processing; Biochemicals; Chip Activation.

    IRI Connections:

    Saad Bhamla

    Saad Bhamla

    Saad Bhamla

    Assistant Professor

    Saad Bhamla studies biomechanics across species to engineer knowledge and tools that inspire curiosity.

    Saad Bhamla is an assistant professor of biomolecular engineering at Georgia Tech. A self-proclaimed "tinkerer," his lab is a trove of discoveries and inventions that span biology, physics and engineering. His current projects include studying the hydrodynamics of insect urine, worm blob locomotion and ultra-low-cost devices for global health. His work has appeared in the New York Times, the Economist, CNN, Wired, NPR, the Wall Street Journal and more.

    Saad is a prolific inventor and his most notable inventions includes a 20-cent paper centrifuge, a 23-cent electroporator, and the 96-cent hearing aid. Saad's work is recognised by numerous awards including a NIH R35 Outstanding Investigator Award, NSF CAREER Award, CTL/BP Junior Faculty Teaching Excellence Award, and INDEX: Design to Improve Life Award. Saad is also a National Geographic Explorer and a TED speaker. Newsweek recognized Saad as 1 of 10 Innovators disrupting healthcare.

    Saad is a co-founder of Piezo Therapeutics.

    Outside of the lab, Saad loves to go hiking with his partner and two dogs (Ollie and Bella).

    saadb@chbe.gatech.edu

    404-894-2856

    Office Location:
    ES&T L1224

    Website

  • Related Site
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    Research Focus Areas:
    • Biobased Materials
    • Biochemicals
    • Biomaterials
    • Biorefining
    • Biotechnology
    • Molecular, Cellular and Tissue Biomechanics
    • Pulp Paper Packaging & Tissue
    • Sustainable Manufacturing
    Additional Research:

    Biotechnology; Complex Systems; Materials and Nanotechnology. The Bhamla Lab explores fundamental and applied research questions through the development of new experimental tools and techniques at the intersection of soft matter, organismic physics and global health. Ultra-fast Organismic Physics Biologists are just starting to systematically examine ultrafast motion across species (jellyfish, mantis shrimp, trap-jaw ants), some of which achieve accelerations exceeding a million g-forces in nanoseconds. At the single-cell level, the physical biology of ultra-fast motility remains poorly understood. What is the fastest motion a single cell can achieve? How do single-cell organisms amplify power and survive repeated high accelerations? These fundamental questions guide our exploration of several non-model unicellular and multicellular organisms to uncover the principles of extreme motility at cellular scales. Biological Soft Matter Our bodies are composed almost entirely of soft, wet, squishy materials. How do the fundamental principles of soft matter and complex fluids enable us to grasp dynamic processes, from the self-assembly of proteins to the stretching of a spider web? We study a spectrum of biological soft matter, from the tears on our eyes to biological foams from insects, with the goal of connecting the microscale structures (lipids, proteins) to their consequences for macroscale biological function (contact lens-eye interaction, microbiome health). As engineers, we leverage this understanding for human-health applications, ranging from diagnostics and monitoring to artificial therapeutic replacements and biomedical devices. Frugal Science and GlobalHealth Today, although information is free to anyone with internet, access to scientific tools and healthcare devices still has many barriers. How do we design and build tools that are scientifically rigorous, but cost a few cents on the dollar? Driven by the spirit of doing “frugal science”, we box ourselves in to find out of the box solutions for global challenges in science education, agriculture, and healthcare. Projects in this area include field-work, science outreach, and citizen-science initiatives. Disciplines: Biotechnology Complex Systems Materials and Nanotechnology


    IRI Connections:

    Jacob Berchuck


    Jacob Berchuck

    Assistant Professor of Hematology and Medical Oncology

    Dr. Jacob Berchuck is a Medical Oncologist at the Winship Cancer Institute and Assistant Professor in the Department of Hematology and Medical Oncology at Emory University School of Medicine. Prior to joining Emory, Dr. Berchuck was an Assistant Professor of Medicine at Harvard Medical School and a Medical Oncologist at the Dana-Farber Cancer Institute. In addition to caring for patients, Dr. Berchuck leads a translational research lab focused on utilizing "liquid biopsy" tools that enable multi-omic profiling of tumor-derived cell-free DNA circulating in the bloodstream to pioneer advances that transform how we manage and treat individuals living with cancer. The core research objectives of the Berchuck Lab include include developing biomarkers to guide treatment decisions, working towards a future where a simple blood draw can enable real-time insights to choose the right treatment for the right patient at the right time, and studying mechanisms of therapeutic resistance. Dr. Berchuck’s research has been published in several high-impact journals, including Nature Medicine, Cancer Cell, Annals of Oncology, JAMA Oncology, Clinical Cancer Research, and others.

    jberchuck@emory.edu

    https://www.theberchucklab.org/

    University, College, and School/Department
    Additional Research:

    Cancer Biology, Diagnostics


    IRI Connections:

    Doby Rahnev

    Rahnev

    Doby Rahnev

    Associate Professor

    Dr. Rahnev received his Ph.D. in Psychology from Columbia University in 2012. After completing a 3-year post-doctoral fellowship at UC Berkeley, he joined Georgia Tech in 2015 where he is currently Blanchard Early Career professor. His research focuses on perceptual decision making – the process of internally representing the available sensory information and making decisions on it. Dr. Rahnev uses a wide variety of methods such as functional magnetic resonance imaging (fMRI), transcranial magnetic stimulation (TMS), psychophysics, computational modeling, and deep neural networks (DNNs). Dr. Rahnev’s work appears in high-impact journals such as Behavioral and Brain Sciences, PNAS, Nature Communications, and Nature Human Behavior. He has received over $3.5M in funding, including PI grants from NIH, NSF, and the Office of Naval Research.

    rahnev@psych.gatech.edu

    Office Location:
    J.S. Coon 130

    https://rahnevlab.gatech.edu/

    University, College, and School/Department
    Additional Research:

    Big Data

    Human Augmentation 


    IRI Connections:

    Anna Ivanova

    Anna Ivanova

    Anna Ivanova

    Assistant Professor of Psychology

    Anna (Anya) Ivanova is an Assistant Professor of Psychology at Georgia Institute of Technology. She got her Ph.D. from MIT’s Department of Brain and Cognitive Science and carried out her postdoctoral training at MIT Quest for Intelligence. In her research, Anya is examining the language-thought relationship in humans and in large language models using a synergistic combination of human brain imaging, behavioral studies, and computational modeling.

    a.ivanova@gatech.edu

    https://www.language-intelligence-thought.net/

    University, College, and School/Department

    IRI Connections:

    Alexander T. Adams

    Alexander Adams

    Alexander Adams

    Assistant Professor

    Alex Adams’s research focuses on designing, fabricating, and implementing new ubiquitous and wearable sensing systems. In particular, he is interested in how to develop these systems using equity-driven design principles for healthcare. Alex leverages sensing, signal processing, and fabrication techniques to design, deploy, and evaluate novel sensing technologies.

    Originally a musician, Alex became fascinated by how he could capture and manipulate sounds through analog hardware and digital signal processing, which led him back to his hometown (Concord, NC). Alex completed his BS at the University of North Carolina at Charlotte in 2014 and his Ph.D. at Cornell University in 2021 (advised by Professor Tanzeem Choudhury). Alex then became the resident Research Scientist for the Precision Behavioral Health Initiative at Cornell Tech (NYC) until the fall of 2022, when he joined the School of Interactive Computing at the Georgia Institute of Technology. Currently, his research focuses on the equity-driven design and the development of multi-modal sensing systems to simultaneously assess mental and physical health to enable a new class of mobile health technologies.

    aadams322@gatech.edu

    7044671939

    Office Location:
    237 TSRB

    https://www.uncommonsenselabs.com

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    Research Focus Areas:
    • Biotechnology
    • Diagnostics
    • Health & Life Sciences
    • Healthcare
    • Machine Learning
    • Medical Device Design, Development and Delivery
    • Optics & Photonics
    • Public Health
    • Robotics
    • Soft Robotics

    IRI Connections: