Andrei Fedorov

Andrei Fedorov

Andrei Fedorov

Professor and Rae S. and Frank H. Neely Chair, Woodruff School Mechanical Engineering
Associate Chair for Graduate Studies, School Mechanical Engineering
Director, Fedorov Lab

Fedorov's background is in thermal/fluid sciences, chemical reaction engineering as well as in applied mathematics. His laboratory works at the intersection between mechanical and chemical engineering and solid state physics and analytical chemistry with the focus on portable/ distributed power generation with synergetic CO2 capture; thermal management of high power dissipation devices and electronics cooling; special surfaces and nanostructured interfaces for catalysis, heat and moisture management; and development of novel bioanalytical instrumentation and chemical sensors. Fedorov joined Georgia Tech in 2000 as an assistant professor after finishing his postdoctoral work at Purdue University.

AGF@gatech.edu

404.385.1356

Office Location:
Love 307

Fedorov Lab

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    Research Focus Areas:
    • Cancer Biology
    • Conventional Energy
    • Drug Design, Development and Delivery
    • Electronic Materials
    • Fuels & Chemical Processing
    • Hydrogen Production
    • Hydrogen Storage & Transport
    • Hydrogen Utilization
    • Materials for Energy
    • Miniaturization & Integration
    • Nuclear
    • Regenerative Medicine
    • Systems Biology
    • Use & Conservation
    Additional Research:

    Heat Transfer; power generation; CO2 Capture; Catalysis; fuel cells; "Fedorov's research is at the interface of basic sciences and engineering. His research portfolio is diverse, covering the areas of portable/ distributed power generation with synergetic carbon dioxide management, including hydrogen/CO2 separation/capture and energy storage, novel approaches to nanomanufacturing (see Figure), microdevices (MEMS) and instrumentation for biomedical research, and thermal management of high performance electronics. Fedorov's research includes experimental and theoretical components, as he seeks to develop innovative design solutions for the engineering systems whose optimal operation and enhanced functionality require fundamental understanding of thermal/fluid sciences. Applications of Fedorov's research range from fuel reformation and hydrogen generation for fuel cells to cooling of computer chips, from lab-on-a-chip microarrays for high throughput biomedical analysis to mechanosensing and biochemical imaging of biological membranes on nanoscale. The graduate and undergraduate students working with Fedorov's lab have a unique opportunity to develop skills in a number of disciplines in addition to traditional thermal/fluid sciences because of the highly interdisciplinary nature of their thesis research. Most students take courses and perform experimental and theoretical research in chemical engineering and applied physics. Acquired knowledge and skills are essential to starting and developing a successful career in academia as well as in many industries ranging from automotive, petrochemical and manufacturing to electronics to bioanalytical instrumentation and MEMS."


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    Constantine Dovrolis

    Constantine Dovrolis

    Constantine Dovrolis

    Professor
    For more than a decade, Constantine Dovrolis has been exploring the evolution of our interconnected world. Dovrolis serves as a Professor in the School of Computer Science, College of Computing at the Georgia Institute of Technology and is an affiliate of the Institute for Information Security & Privacy. He received his Bachelor's of Computer Engineering from the Technical University of Crete in 1995; Master’s degree from the University of Rochester in 1996, and his Doctoral degree from the University of Wisconsin-Madison in 2000.  Prior to joining Georgia Tech in August 2002, Dovrolis held visiting positions at Thomson Research in Paris, Simula Research in Oslo, and FORTH in Crete. His current research focuses on the evolution of the Internet, Internet economics, and on applications of network measurement.  He also is interested in cross-disciplinary applications of network science as it relates to biology, clIMaTe science and neuroscience. Dovrolis has served as an editor for the IEEE/ACM’s Transactions on Networking, the ACM Communications Review, and he served as the program co-chair for PAM'05, IMC'07, CoNEXT'11, and as the general chair for HotNets'07.  He was honored with the National Science Foundation CAREER Award in 2003.                                                   

    constantine@gatech.edu

    404-385-4205

    Office Location:
    Klaus 3346

    Website

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    Research Focus Areas:
    • Neuroscience
    • Systems Biology
    Additional Research:
    Data Mining & Analytics; IT Economics; Internet Infrastructure & Operating Systems Network science is an emerging discipline focusing on the analysis and design of complex systems that can be modeled as networks. During the last decade or so network science has attracted physicists, mathematicians, biologists, neuroscientists, engineers, and of course computer scientists. I believe that this area has the potential to create major scientific breakthroughs, especially because it is highly interdisciplinary. We have applied network science methods to investigate the "hourglass effect" in developmental biology. The developmental hourglass' describes a pattern of increasing morphological divergence towards earlier and later embryonic development, separated by a period of significant conservation across distant species (the "phylotypic stage''). Recent studies have found evidence in support of the hourglass effect at the genomic level. For instance, the phylotypic stage expresses the oldest and most conserved transcriptomes. However, the regulatory mechanism that causes the hourglass pattern remains an open question. We have used an evolutionary model of regulatory gene interactions during development to identify the conditions under which the hourglass effect can emerge in a general setting. The model focuses on the hierarchical gene regulatory network that controls the developmental process, and on the evolution of a population under random perturbations in the structure of that network. The model predicts, under fairly general assumptions, the emergence of an hourglass pattern in the structure of a temporal representation of the underlying gene regulatory network. The evolutionary age of the corresponding genes also follows an hourglass pattern, with the oldest genes concentrated at the hourglass waist. The key behind the hourglass effect is that developmental regulators should have an increasingly specific function as development progresses. Analysis of developmental gene expression profiles from Drosophila melanogaster and Arabidopsis thaliana provide consistent results with our theoretical predictions. We are currently working on the inference and analysis of functional and brain networks. More information about this project will be posted soon.

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    Robert Dickson

    Robert Dickson

    Robert Dickson

    Professor

    Dr. Dickson is the Vassar Woolley Professor of Chemistry & Biochemistry and has been at Georgia Tech since 1998. He was a Senior Editor of The Journal of Physical Chemistry from 2010-2021, and his research has been continuously funded (primarily from NIH) since 2000. Dr. Dickson has developed quantitative bio imaging and signal recovery/modulation schemes for improved imaging of biological processes and detection of medical pathologies. His work on fluorescent molecule development and photoswitching of green fluorescent proteins was recognized as a key paper for W.E. Moerner’s 2014 Nobel Prize in Chemistry. Recently, Dr. Dickson’s lab has developed rapid susceptibility testing of bacteria causing blood stream infections. Their rapid recovery methods, coupled with rigorous multidimensional statistics and machine learning have led to very simple, highly accurate and fast methods for determining the appropriate treatment within a few hours after positive blood cultures. These hold significant potential for drastically improving patient outcomes and reducing the proliferation of antimicrobial resistance.

    robert.dickson@chemistry.gatech.edu

    404-894-4007

    Office Location:
    MoSE G209A

    Website

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    Additional Research:
    Dr. Dickson's group is developing novel spectroscopic, statistical, and imagingtechnologies for the study of dynamics in biology and medicine.

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    Julie Champion

    Julie Champion

    Julie Champion

    Professor, School Chemical and Biomolecular Engineering

    Julie Champion is the William R. McLain Endowed Term Professor in the School of Chemical and Biomolecular Engineering at Georgia Institute of Technology. She earned her B.S.E. in chemical engineering from the University of Michigan and Ph.D. in chemical engineering at the University of California Santa Barbara. She was an NIH postdoctoral fellow at the California Institute of Technology. Champion is a fellow of the American Institute for Medical and Biological Engineering and has received awards including American Chemical Society Women Chemists Committee Rising Star, NSF BRIGE Award, Georgia Tech Women in Engineering Faculty Award for Excellence in Teaching, Georgia Tech BioEngineering Program Outstanding Advisor Award. Professor Champion’s current research focuses on design and self-assembly of functional nanomaterials made from engineered proteins for applications in immunology, cancer, and biocatalysis.

    julie.champion@chbe.gatech.edu

    404.894.2874

    Office Location:
    EBB 5015

    Champion Lab

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    Research Focus Areas:
    • Biobased Materials
    • Biomaterials
    • Cancer Biology
    • Drug Design, Development and Delivery
    • Regenerative Medicine
    Additional Research:

    Cellular Materials; Drug Delivery; Self-Assembly; "Developing therapeutic protein materials, where the protein is both the drug and thedelivery system Engineering proteins to control and understand protein particleself-assembly Repurposing and engineering pathogenic proteins for human therapeutics Creating materials that mimic cell-cell interactions to modulate immunologicalfunctions for various applications, including inflammation, cancer, autoimmune disease, and vaccination"


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    Stefan France

    Stefan France

    Stefan France

    Associate Professor

    Stefan France is an Associate Professor in the School of Chemistry and Biochemistry. Professor France earned his B.S. in Chemistry (2000) from Duke University and a M.A. (2003) and Ph.D. (2005) in Organic Chemistry from Johns Hopkins University. His research group focuses on experimental methodology development, natural product synthesis, and medicinal chemistry. Owing to Prof. France's avid interest in undergraduate research, his research group has mentored and trained more than 60 undergraduates (both Georgia Tech and non-Georgia Tech students). Professor France has been the recipient of several awards for his research, mentorship, and teaching including: the 2018 Georgia Tech-Georgia Power Professor of Excellence; the 2015 Georgia Tech Senior Faculty Outstanding Undergraduate Mentor Award; the 2014 Georgia Tech Faculty Award for Academic Outreach; the 2014 Georgia Tech Hesberg Teaching Award; the 2013 Georgia Tech Sigma Xi Young Faculty Award; the 2012 National Organization for the Professional Advancement for Black Chemists and Chemical Engineers (NOBCChE) Lloyd N. Ferguson Young Scientist Award; and the 2011 National Science Foundation (NSF) CAREER Award. He heads the Chemistry FAST Program, a NSF Research Experiences for Undergraduates (REU) Site, and also serves as Chair of the NSF Chemistry REU Leadership Group.

    stefan.france@chemistry.gatech.edu

    404-385-1796

    Office Location:
    MoSE 2100K

    Website

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    Research Focus Areas:
    • Cancer Biology
    • Drug Design, Development and Delivery
    Additional Research:
    Our group is interested in the design of efficient methodologies to accomplish the formation of carbon-carbon and carbon-heteroatom bonds with the intent to apply the methodology toward the synthesis of complex natural and unnatural targets. Natural Product Synthesis. Approaches to natural products not only inspire the development of new synthetic strategies, but often unveil unexpected and often interesting reactivity. Targets are chosen for their interesting biological activity along with their sheer complexity. We are interested in exploring both modular and convergent approaches to complex targets that enable facile derivatization for the development of combinatorial libraries. Medicinal Chemistry. Medicinal or pharmaceutical chemistry lies at the intersection of chemistry and pharmacy. Our group is interested in the design, synthesis and development of pharmaceutical drugs, or other chemical entities suitable for therapeutic use. We are further interested in the study of their biological properties and their quantitative structure-activity relationships (QSAR). Given that medicinal chemistry is a highly interdisciplinary science, we aim to establish several collaborations with biologists, biochemists, and computational chemists to facilitate the design and development process. In particular, we aim to develop therapeutics toward the treatment of various forms of cancer, HIV, diabetes, and neurological disorders, such as Alzheimer's and Parkinson's disease.

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    M.G. Finn


    M.G. Finn

    Professor, James A. Carlos Family Chair for Pediatric Technology

    mgfinn@gatech.edu

    404-385-0906

    Office Location:
    MoSE 2201B

    Website

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    Research Focus Areas:
    • Biomaterials
    • Drug Design, Development and Delivery
    • Molecular Evolution
    Additional Research:

    We develop chemical and biological tools for research in a wide range of fields. Some of them are briefly described below; please see our group web page for more details. Chemistry, biology, immunology, and evolution with viruses. The sizes and properties of virus particles put them at the interface between the worlds of chemistry and biology. We use techniques from both fields to tailor these particles for applications to cell targeting, diagnostics, vaccine development, catalysis, and materials self-assembly. This work involves combinations of small-molecule and polymer synthesis, bioconjugation, molecular biology, protein design, protein evolution, bioanalytical chemistry, enzymology, physiology, and immunology. It is an exciting training ground for modern molecular scientists and engineers. Development of reactions for organic synthesis, chemical biology, and materials science. Molecular function is what matters most to our scientific lives, and good chemical reactions provide the means to achieve such function. We continue our efforts to develop and optimize reactions that meet the click chemistry standard for power and generality. Our current focus is on highly reliable reversible reactions, which open up new possibilities for polymer synthesis and modification, as well as for the controlled delivery of therapeutic and diagnostic agents to biological targets. Traditional and combinatorial synthesis of biologically active compounds.We have a longstanding interest in the development of biologically active small molecules. We work closely with industrial and academic collaborators on such targets as antiviral agents, compounds to combat tobacco addiction, and treatments for inflammatory disease.


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    Flavio Fenton

    Flavio Fenton

    Flavio Fenton

    Professor

    flavio.fenton@physics.gatech.edu

    516-672-6003

    Office Location:
    Howey N05

    Website

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    University, College, and School/Department
    Research Focus Areas:
    • High Performance Computing
    Additional Research:
    High performance computing: ·Development and implementation of novel algorithms to solve partial differential equations in two- and three-dimensional regular and irregular domains. ·Computer modeling of complex systems using supercomputers, as well as graphics cards (GPUs). ·Simulations and large data visualization of complex systems in or near-real time locally or over the web. Experiments in complex systems: ·Cardiac dynamics.Study the voltage and calcium dynamics of cardiac tissue using heart sections or whole hearts from fish and mice to large mamals horses. Using voltage- and calcium-sensitive dyes and ultrafast cameras, we record the dynamics of voltage and calcium waves and study their instabilities associated with arrhythmias. ·Dynamics of spiral and scroll waves. ·Mechanisms of bifurcation and period-doublings in time and in space. ·Methods for chaos control and synchronization. ·Chemical, physical, and other biophysical oscillators with complex dynamics and instabilities. Examples: spiral and scroll waves in the Belousov–Zhabotinsky reaction, saline oscillator. Mathematical modeling of complex systems: ·Development and analysis of mathematical models that describe generic or detailed dynamics of excitable and oscillatory media (heart, neurons, chemical reactions, calcium signaling, physical and biological oscillators, etc.). ·Study of bifurcations and chaotic (organized and disorganized) dynamics of excitable and oscillatory systems. ·Develop and apply control methods for suppressing or synchronizing complex dynamics. ·Study of stability and instabilities of spiral waves and three-dimensional scroll waves in idealized and realistic domains of excitable media. In most projects there is crossover between theory, simulations and experiments, where experiments (simulations) are used to guide theory and simulations (experiments).

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    Jaydev Desai

    Jaydev Desai

    Jaydev Desai

    Professor and Distinguished Faculty Fellow, Wallace H. Coulter Department of Biomedical Engineering
    Associate Director, Institute for Robotics and Intelligent Machines
    Director, Georgia Center for Medical Robotics

    Jaydev P. Desai, Ph.D, is currently a Professor and BME Distinguished Faculty Fellow in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech. Prior to joining Georgia Tech in August 2016, he was a Professor in the Department of Mechanical Engineering at the University of Maryland, College Park (UMCP). He completed his undergraduate studies from the Indian Institute of Technology, Bombay, India, in 1993. He received his M.A. in Mathematics in 1997, M.S. and Ph.D. in Mechanical Engineering and Applied Mechanics in 1995 and 1998 respectively, all from the University of Pennsylvania. He was also a Post-Doctoral Fellow in the Division of Engineering and Applied Sciences at Harvard University. He is a recipient of several NIH R01 grants, NSF CAREER award, and was also the lead inventor on the "Outstanding Invention of 2007 in Physical Science Category" at the University of Maryland, College Park. He is also the recipient of the Ralph R. Teetor Educational Award. In 2011, he was an invited speaker at the National Academy of Sciences "Distinctive Voices" seminar series on the topic of "Robot-Assisted Neurosurgery" at the Beckman Center. He was also invited to attend the National Academy of Engineering's 2011 U.S. Frontiers of Engineering Symposium. He has over 150 publications, is the founding Editor-in-Chief of the Journal of Medical Robotics Research, and Editor-in-Chief of the Encyclopedia of Medical Robotics (currently in preparation). His research interests are primarily in the area of image-guided surgical robotics, rehabilitation robotics, cancer diagnosis at the micro-scale, and rehabilitation robotics. He is a Fellow of the ASME and AIMBE.

    jaydev@gatech.edu

    404.385.5381

    Office Location:
    UA Whitaker Room 3112

    Website

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    Research Focus Areas:
    • Cancer Biology
    • Human Augmentation
    • Miniaturization & Integration
    • Neuroscience
    Additional Research:

    Image-guided surgical robotics, Rehabilitation robotics; Cancer diagnosis at the micro-scale.


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    Suman Das

    Suman Das

    Suman Das

    Morris M. Bryan, Jr. Chair and Professor, Woodruff School of Mechanical Engineering
    Director, Direct Digital Manufacturing Laboratory

    suman.das@me.gatech.edu

    404.385.6027

    Office Location:
    MARC 255

    Direct Digital Manufacturing Laboratory

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    Research Focus Areas:
    • Additive manufacturing
    • Biomaterials
    • Conventional Energy
    • Materials and Nanotechnology
    Additional Research:

    3D printing; Additive/Advanced Manufacturing; Biomaterials; Composites; Emerging Technologies; Nanocomposites; Nanomanufacturing; Manufacturing, Mechanics of Materials, Bioengineering, and Micro and Nano Engineering. Advanced manufacturing and materials processing of metallic, polymeric, ceramic, and composite materials for applications in life sciences, propulsion, and energy. Professor Das directs the Direct Digital Manufacturing Laboratory and Research Group at Georgia Tech. His research interests encompass a broad variety of interdisciplinary topics under the overall framework of advanced design, prototyping, direct digital manufacturing, and materials processing particularly to address emerging research issues in life sciences, propulsion, and energy. His ultIMaTe objectives are to investigate the science and design of innovative processing techniques for advanced materials and to invent new manufacturing methods for fabricating devices with unprecedented functionality that can yield dramatic improvements in performance, properties and costs.


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    Jennifer Curtis

    Jennifer Curtis

    Jennifer Curtis

    Professor, School of Physics

    The Curtis lab is primarily focused on the physics of cell-cell and cell-extracellular matrix interactions, in particular within the context of glycobiology and immunobiology. Our newest projects focus on questions of collective and single cell migration in vitro and in vivo; immunophage therapy "an immunoengineering approach - that uses combined defense of immune cells plus viruses (phage) to overcome bacterial infections"; and the study of the molecular biophysics and biomaterials applications of the incredible enzyme, hyaluronan synthase. A few common scientific themes emerge frequently in our projects: biophysics at interfaces, the use of quantitative modeling, collective interactions of cells and/or molecules, cell mechanics, cell motility and adhesion, and in many cases, the role of bulky sugars in facilitating cell integration and rearrangements in tissues.

    jcurtis6@gatech.edu

    404.894.8839

    Office Location:
    MoSE G024/G128

    Cell Physics Laboratory

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    University, College, and School/Department
    Research Focus Areas:
    • Biobased Materials
    • Biomaterials
    • Molecular, Cellular and Tissue Biomechanics
    Additional Research:

    Advanced characterization, cell biophysics, soft materials, tissue engineering, cell biophysics, cell mechanics of adhesion, migration and dynamics, immunophysics, immunoengineering, hyaluronan glycobiology, hyaluronan synthase, physics of tissues


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