Vinayak Agarwal

Vinayak Agarwal
vagarwal@gatech.edu
Website

Vinny is an Assistant Professor at Georgia Tech with joint appointments at the School of Chemistry and Biochemistry and School of Biological Sciences.

A majority of antibiotics and drugs that we use in the clinic are derived or inspired from small organic molecules called Natural Products that are produced by living organisms such as bacteria and plants. Natural Products are at the forefront of fighting the global epidemic of antibiotic resistant pathogens, and keeping the inventory of clinically applicable pharmaceuticals stocked up. Some Natural Products are also potent human toxins and pollutants, and we need to understand how these toxins are produced to minimize our and the environmental exposure to them.

We as biochemists ask some simple questions- how and why are Natural Products produced in Nature, what we can learn from Natural Product biosynthetic processes, and how we can exploit Nature's synthetic capabilities for interesting applications?

Broadly, we are interested in questions involving (meta)genomics, biochemistry, structural and mechanistic enzymology, mass spectrometry, analytical chemistry, and how natural product chemistry dictates biology.

Assistant Professor
Phone
404-385-3798
Office
Petit Biotechnology Building, Office 3315
Additional Research

A majority of antibiotics and drugs that we use in the clinic are derived or inspired from small organic molecules called Natural Products that are produced by living organisms such as bacteria and plants. Natural Products are at the forefront of fighting the global epidemic of antibiotic resistant pathogens, and keeping the inventory of clinically applicable pharmaceuticals stocked up. Some Natural Products are also potent human toxins and pollutants, and we need to understand how these toxins are produced to minimize our and the environmental exposure to them. We as biochemists ask some simple questions- how and why are Natural Products produced in Nature, what we can learn from Natural Product biosynthetic processes, and how we can exploit Nature's synthetic capabilities for interesting applications? Broadly, we are interested in questions involving (meta)genomics, biochemistry, structural and mechanistic enzymology, mass spectrometry, analytical chemistry, and how natural product chemistry dictates biology.

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Alexander T. Adams

Alexander Adams
aadams322@gatech.edu
https://www.uncommonsenselabs.com

Alex Adams’s research focuses on designing, fabricating, and implementing new ubiquitous and wearable sensing systems. In particular, he is interested in how to develop these systems using equity-driven design principles for healthcare. Alex leverages sensing, signal processing, and fabrication techniques to design, deploy, and evaluate novel sensing technologies.

Originally a musician, Alex became fascinated by how he could capture and manipulate sounds through analog hardware and digital signal processing, which led him back to his hometown (Concord, NC). Alex completed his BS at the University of North Carolina at Charlotte in 2014 and his Ph.D. at Cornell University in 2021 (advised by Professor Tanzeem Choudhury). Alex then became the resident Research Scientist for the Precision Behavioral Health Initiative at Cornell Tech (NYC) until the fall of 2022, when he joined the School of Interactive Computing at the Georgia Institute of Technology. Currently, his research focuses on the equity-driven design and the development of multi-modal sensing systems to simultaneously assess mental and physical health to enable a new class of mobile health technologies.

Assistant Professor
Office
237 TSRB
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Alex Abramson

Alex Abramson
aabramson6@gatech.edu
Abramson Lab

Alex Abramson is an assistant professor in the School of Chemical and Biomolecular Engineering at Georgia Tech. His research, which focuses on drug delivery and bioelectronic therapeutics, has been featured in news outlets such as The New York Times, NPR, and Wired. Abramson has received several recognitions for scientific innovation, including being named a member of the Forbes 30 Under 30 Science List and the MIT Technology Review Innovators Under 35 List. He is passionate about translating scientific endeavors from bench to bedside. Large pharmaceutical companies have exclusively licensed a portfolio of his patents to bring into clinical trials, and Abramson serves as a scientific advisor overseeing their commercialization. In addition to his scientific endeavors, Abramson plays an active role in his community by leading diversity and inclusion efforts on campus and volunteering as a STEM tutor to local students.

Abramson received a B.S. in chemical and biomolecular engineering from Johns Hopkins University and a Ph.D. in chemical engineering from MIT as an NSF Graduate Research Fellow under the direction of Professors Robert Langer and Giovanni Traverso. He conducted postdoctoral work at Stanford University as an NIH fellow with Professors Zhenan Bao and the late Sanjiv S. Gambhir.

The Abramson Lab develops ingestible, implantable, and wearable robotic therapeutic devices that solve key healthcare problems and provide measurable therapeutic outcomes. Our translationally focused research spans a multitude of areas, including (1) drug delivery devices for optimal drug adherence, (2) soft materials for bioelectronic sensors and therapeutics, and (3) preclinical drug screening technologies.

Assistant Professor, School of Chemical and Biomolecular Engineering
Office
MoSE 4120B
Additional Research
  • Biosensors
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Joscelyn Mejias

Joscelyn Mejias
joscelyn.mejias@bme.gatech.edu

Joscelyn Mejías is an assistant professor in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University. She received a BS in bioengineering with the Distinction in Research and Creative Works and a BA in asian studies from Rice University; she earned her MS and Ph.D. from the joint Wallace H. Coulter Department of Biomedical Engineering at the Georgia Institute of Technology and Emory University. Mejías has been supported by a number of awards including the GT Presidents Fellowship and Goizueta Foundation Fellowship, NSF-GRFP, and Alfred P. Sloan Foundations Minority Ph.D. Fellowship. She has received the 2023 L’Oréal For Women in Science for her work in Uterine Fibroids and NIA MOSAIC K99 to study age and sex differences in the immune response to biomaterials. Her lab focuses on biomaterials, immune mediated tissue regeneration, and developing in vitro models of fibrosis (uterine fibroids).

Assistant Professor
Office
UAW 3121
Mejías Lab
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J. Lucas Mckay

JM
jmckay2@emory.edu
https://jlucasmckay.bmi.emory.edu/

Dr. J. Lucas Mckay, PhD MSCR, is an Associate Professor of Biomedical Informatics and Neurology at Emory University School of Medicine. He earned his PhD in Electrical and Computer Engineering from Georgia Tech and a Master’s in Clinical Research Methods. He co‑directs the Emory Brain Health Center Motion Analysis Lab and maintains one of the largest full‑body behavioral data repositories for movement disorders. His translational research focuses on balance, gait, falls, and freezing of gait in Parkinson’s disease, bridging engineering, biostatistics, and clinical trials. He serves as a biostatistician on federally funded Parkinson’s and Alzheimer’s disease trials and holds NIH career development awards, with a strong record of interdisciplinary collaboration and peer‑reviewed publications.

Associate Professor
Office
Emory Brain Health Center
Additional Research
  • Bioinformatics
  • Healthcare
  • Other
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Craig Forest

Craig Forest
cforest@gatech.edu
Website

Craig Forest is a Professor and Woodruff Faculty Fellow in the George W. Woodruff School of Mechanical Engineering at Georgia Tech where he also holds program faculty positions in Bioengineering and Biomedical Engineering. He conducts research on miniaturized, high-throughput robotic instrumentation to advance neuroscience and genetic science, working at the intersection of bioMEMS, precision machine design, optics, and microfabrication. Prior to Georgia Tech, he was a research fellow in Genetics at Harvard Medical School. He obtained a Ph.D. in Mechanical Engineering from MIT in June 2007, M.S. in Mechanical Engineering from MIT in 2003, and B.S. in Mechanical Engineering from Georgia Tech in 2001. He is cofounder/organizer of one of the largest undergraduate invention competitions in the US—The InVenture Prize, and founder/organizer of one of the largest student-run makerspaces in the US—The Invention Studio. He was a recently a Fellow in residence at the Allen Insitutte for Brain Science in Seattle WA; he was awarded the Georgia Tech Institute for BioEngineering and BioSciences Junior Faculty Award (2010) and was named Engineer of the Year in Education for the state of Georgia (2013). He is one of the inaugural recipients of the NIH BRAIN Initiative Grants, a national effort to invent the next generation of neuroscience and neuroengineering tools. In 2007, he was a finalist on the ABC reality TV show "American Inventor.”

Professor
Phone
404.385.7645
Office
Petit Biotechnology Building, Office 1310
Additional Research
The Precision Biosystems Laboratory is focused on the creation and application of miniaturized, high-throughput, biological instrumentation to advance genetic science. The development of instruments that can nimbly load, manipulate, and measure many biological samples - not only simultaneously, but also more sensitively, more accurately, and more repeatably than under current approaches - opens the door to essential, comprehensive biological system studies. Our group strives to develop these tools, validate their performance with meaningful biological assays, and with our collaborators, pursue discoveries using the instruments. These instruments, and the discoveries they enable, could open new frontiers forthe design and control of biological systems.
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Andrei Fedorov

Andrei Fedorov
AGF@gatech.edu
Fedorov Lab

Fedorov's background is in thermal/fluid sciences, chemical reaction engineering as well as in applied mathematics. His laboratory works at the intersection between mechanical and chemical engineering and solid state physics and analytical chemistry with the focus on portable/ distributed power generation with synergetic CO2 capture; thermal management of high power dissipation devices and electronics cooling; special surfaces and nanostructured interfaces for catalysis, heat and moisture management; and development of novel bioanalytical instrumentation and chemical sensors. Fedorov joined Georgia Tech in 2000 as an assistant professor after finishing his postdoctoral work at Purdue University.

Professor and Rae S. and Frank H. Neely Chair, Woodruff School Mechanical Engineering
Associate Chair for Graduate Studies, School Mechanical Engineering
Director, Fedorov Lab
Phone
404.385.1356
Office
Love 307
Additional Research

Heat Transfer; power generation; CO2 Capture; Catalysis; fuel cells; "Fedorov's research is at the interface of basic sciences and engineering. His research portfolio is diverse, covering the areas of portable/ distributed power generation with synergetic carbon dioxide management, including hydrogen/CO2 separation/capture and energy storage, novel approaches to nanomanufacturing (see Figure), microdevices (MEMS) and instrumentation for biomedical research, and thermal management of high performance electronics. Fedorov's research includes experimental and theoretical components, as he seeks to develop innovative design solutions for the engineering systems whose optimal operation and enhanced functionality require fundamental understanding of thermal/fluid sciences. Applications of Fedorov's research range from fuel reformation and hydrogen generation for fuel cells to cooling of computer chips, from lab-on-a-chip microarrays for high throughput biomedical analysis to mechanosensing and biochemical imaging of biological membranes on nanoscale. The graduate and undergraduate students working with Fedorov's lab have a unique opportunity to develop skills in a number of disciplines in addition to traditional thermal/fluid sciences because of the highly interdisciplinary nature of their thesis research. Most students take courses and perform experimental and theoretical research in chemical engineering and applied physics. Acquired knowledge and skills are essential to starting and developing a successful career in academia as well as in many industries ranging from automotive, petrochemical and manufacturing to electronics to bioanalytical instrumentation and MEMS."

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Constantine Dovrolis

Constantine Dovrolis
constantine@gatech.edu
Website
For more than a decade, Constantine Dovrolis has been exploring the evolution of our interconnected world. Dovrolis serves as a Professor in the School of Computer Science, College of Computing at the Georgia Institute of Technology and is an affiliate of the Institute for Information Security & Privacy. He received his Bachelor's of Computer Engineering from the Technical University of Crete in 1995; Master’s degree from the University of Rochester in 1996, and his Doctoral degree from the University of Wisconsin-Madison in 2000.  Prior to joining Georgia Tech in August 2002, Dovrolis held visiting positions at Thomson Research in Paris, Simula Research in Oslo, and FORTH in Crete. His current research focuses on the evolution of the Internet, Internet economics, and on applications of network measurement.  He also is interested in cross-disciplinary applications of network science as it relates to biology, clIMaTe science and neuroscience. Dovrolis has served as an editor for the IEEE/ACM’s Transactions on Networking, the ACM Communications Review, and he served as the program co-chair for PAM'05, IMC'07, CoNEXT'11, and as the general chair for HotNets'07.  He was honored with the National Science Foundation CAREER Award in 2003.                                                   
Professor
Phone
404-385-4205
Office
Klaus 3346
Additional Research
Data Mining & Analytics; IT Economics; Internet Infrastructure & Operating Systems Network science is an emerging discipline focusing on the analysis and design of complex systems that can be modeled as networks. During the last decade or so network science has attracted physicists, mathematicians, biologists, neuroscientists, engineers, and of course computer scientists. I believe that this area has the potential to create major scientific breakthroughs, especially because it is highly interdisciplinary. We have applied network science methods to investigate the "hourglass effect" in developmental biology. The developmental hourglass' describes a pattern of increasing morphological divergence towards earlier and later embryonic development, separated by a period of significant conservation across distant species (the "phylotypic stage''). Recent studies have found evidence in support of the hourglass effect at the genomic level. For instance, the phylotypic stage expresses the oldest and most conserved transcriptomes. However, the regulatory mechanism that causes the hourglass pattern remains an open question. We have used an evolutionary model of regulatory gene interactions during development to identify the conditions under which the hourglass effect can emerge in a general setting. The model focuses on the hierarchical gene regulatory network that controls the developmental process, and on the evolution of a population under random perturbations in the structure of that network. The model predicts, under fairly general assumptions, the emergence of an hourglass pattern in the structure of a temporal representation of the underlying gene regulatory network. The evolutionary age of the corresponding genes also follows an hourglass pattern, with the oldest genes concentrated at the hourglass waist. The key behind the hourglass effect is that developmental regulators should have an increasingly specific function as development progresses. Analysis of developmental gene expression profiles from Drosophila melanogaster and Arabidopsis thaliana provide consistent results with our theoretical predictions. We are currently working on the inference and analysis of functional and brain networks. More information about this project will be posted soon.
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Stefan France

Stefan France
stefan.france@chemistry.gatech.edu
Website

Stefan France is an Associate Professor in the School of Chemistry and Biochemistry. Professor France earned his B.S. in Chemistry (2000) from Duke University and a M.A. (2003) and Ph.D. (2005) in Organic Chemistry from Johns Hopkins University. His research group focuses on experimental methodology development, natural product synthesis, and medicinal chemistry. Owing to Prof. France's avid interest in undergraduate research, his research group has mentored and trained more than 60 undergraduates (both Georgia Tech and non-Georgia Tech students). Professor France has been the recipient of several awards for his research, mentorship, and teaching including: the 2018 Georgia Tech-Georgia Power Professor of Excellence; the 2015 Georgia Tech Senior Faculty Outstanding Undergraduate Mentor Award; the 2014 Georgia Tech Faculty Award for Academic Outreach; the 2014 Georgia Tech Hesberg Teaching Award; the 2013 Georgia Tech Sigma Xi Young Faculty Award; the 2012 National Organization for the Professional Advancement for Black Chemists and Chemical Engineers (NOBCChE) Lloyd N. Ferguson Young Scientist Award; and the 2011 National Science Foundation (NSF) CAREER Award. He heads the Chemistry FAST Program, a NSF Research Experiences for Undergraduates (REU) Site, and also serves as Chair of the NSF Chemistry REU Leadership Group.

Associate Professor
Phone
404-385-1796
Office
MoSE 2100K
Additional Research
Our group is interested in the design of efficient methodologies to accomplish the formation of carbon-carbon and carbon-heteroatom bonds with the intent to apply the methodology toward the synthesis of complex natural and unnatural targets. Natural Product Synthesis. Approaches to natural products not only inspire the development of new synthetic strategies, but often unveil unexpected and often interesting reactivity. Targets are chosen for their interesting biological activity along with their sheer complexity. We are interested in exploring both modular and convergent approaches to complex targets that enable facile derivatization for the development of combinatorial libraries. Medicinal Chemistry. Medicinal or pharmaceutical chemistry lies at the intersection of chemistry and pharmacy. Our group is interested in the design, synthesis and development of pharmaceutical drugs, or other chemical entities suitable for therapeutic use. We are further interested in the study of their biological properties and their quantitative structure-activity relationships (QSAR). Given that medicinal chemistry is a highly interdisciplinary science, we aim to establish several collaborations with biologists, biochemists, and computational chemists to facilitate the design and development process. In particular, we aim to develop therapeutics toward the treatment of various forms of cancer, HIV, diabetes, and neurological disorders, such as Alzheimer's and Parkinson's disease.
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M.G. Finn

mgfinn@gatech.edu
Website
Professor, James A. Carlos Family Chair for Pediatric Technology
Phone
404-385-0906
Office
MoSE 2201B
Additional Research

We develop chemical and biological tools for research in a wide range of fields. Some of them are briefly described below; please see our group web page for more details. Chemistry, biology, immunology, and evolution with viruses. The sizes and properties of virus particles put them at the interface between the worlds of chemistry and biology. We use techniques from both fields to tailor these particles for applications to cell targeting, diagnostics, vaccine development, catalysis, and materials self-assembly. This work involves combinations of small-molecule and polymer synthesis, bioconjugation, molecular biology, protein design, protein evolution, bioanalytical chemistry, enzymology, physiology, and immunology. It is an exciting training ground for modern molecular scientists and engineers. Development of reactions for organic synthesis, chemical biology, and materials science. Molecular function is what matters most to our scientific lives, and good chemical reactions provide the means to achieve such function. We continue our efforts to develop and optimize reactions that meet the click chemistry standard for power and generality. Our current focus is on highly reliable reversible reactions, which open up new possibilities for polymer synthesis and modification, as well as for the controlled delivery of therapeutic and diagnostic agents to biological targets. Traditional and combinatorial synthesis of biologically active compounds.We have a longstanding interest in the development of biologically active small molecules. We work closely with industrial and academic collaborators on such targets as antiviral agents, compounds to combat tobacco addiction, and treatments for inflammatory disease.

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