Andreas Bommarius

Andreas Bommarius
andreas.bommarius@chbe.gatech.edu
Website

Andreas (Andy) S. Bommarius is a professor of Chemical and Biomolecular Engineering as well of Chemistry and Biochemistry at the Georgia Institute of Technology in Atlanta, GA.  He received his diploma in Chemistry in 1984 at the Technical University of Munich, Germany and his Chemical Engineering B.S. and Ph.D. degrees in 1982 and 1989 at MIT, Cambridge, MA.

From 1990-2000, he led the Laboratory of Enzyme Catalysis at Degussa (now Evonik) in Wolfgang, Germany, where his work ranged from immobilizing homogenous catalysts in membrane reactors to large-scale cofactor-regenerated redox reactions to pharma intermediates.

At Georgia Tech since 2000, his research interests cover green chemistry and biomolecular engineering, specifically biocatalyst development and protein stability studies.  His lab applies data-driven protein engineering to improve protein properties on catalysts ranging from ene and nitro reductases to cellobiohydrolases.  Bommarius has guided the repositioning of the curriculum towards Chemical and Biomolecular Engineering by developing new courses in Process Design, Biocatalysis and Metabolic Engineering, as well as Drug Design, Development, and Delivery (D4), an interdisciplinary course with Mark Prausnitz.

Andy Bommarius in 2008 became a Fellow of the American Institute of Medical and Biological Engineering.  Since 2010, he is Director of the NSF-I/UCR Center for Pharmaceutical Development (CPD), a Center focusing on process development, drug substance and product stability, and novel analytical methods for the characterization of drug substances and excipients.

Professor, School of Chemical and Biomolecular Engineering, School of Chemistry and Biochemistry
RBI Initiative Lead: A Renewables-based Economy from WOOD (ReWOOD)
Phone
404-385-1334
Office
EBB 5018
Additional Research

Biomolecular engineering, especially biocatalysis, biotransformations, and biocatalyst stability. Biofuels. Enzymatic Processing; Biochemicals; Chip Activation.

Google Scholar
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Sam Brown

Sam Brown
sam.brown@biology.gatech.edu
Website

Sam Brown's lab studies the multi-scale dynamics of infectious disease. Their goal is to improve the treatment and control of infectious diseases through a multi-scale understanding of microbial interactions. Their approach is highly interdisciplinary, combining theory and experiment, evolution, ecology and molecular microbiology in order to understand and control the multi-scale dynamics of bacteria pathogens.

Professor
Office
ES&T 2244
Additional Research
Evolutionary microbiology, bacterial social life, virulence and drug resistance
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http://biosci.gatech.edu/people/sam-brown
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M.G. Finn

mgfinn@gatech.edu
Website
Professor, James A. Carlos Family Chair for Pediatric Technology
Phone
404-385-0906
Office
MoSE 2201B
Additional Research

We develop chemical and biological tools for research in a wide range of fields. Some of them are briefly described below; please see our group web page for more details. Chemistry, biology, immunology, and evolution with viruses. The sizes and properties of virus particles put them at the interface between the worlds of chemistry and biology. We use techniques from both fields to tailor these particles for applications to cell targeting, diagnostics, vaccine development, catalysis, and materials self-assembly. This work involves combinations of small-molecule and polymer synthesis, bioconjugation, molecular biology, protein design, protein evolution, bioanalytical chemistry, enzymology, physiology, and immunology. It is an exciting training ground for modern molecular scientists and engineers. Development of reactions for organic synthesis, chemical biology, and materials science. Molecular function is what matters most to our scientific lives, and good chemical reactions provide the means to achieve such function. We continue our efforts to develop and optimize reactions that meet the click chemistry standard for power and generality. Our current focus is on highly reliable reversible reactions, which open up new possibilities for polymer synthesis and modification, as well as for the controlled delivery of therapeutic and diagnostic agents to biological targets. Traditional and combinatorial synthesis of biologically active compounds.We have a longstanding interest in the development of biologically active small molecules. We work closely with industrial and academic collaborators on such targets as antiviral agents, compounds to combat tobacco addiction, and treatments for inflammatory disease.

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Joseph Lachance

Joseph Lachance
joseph.lachance@biology.gatech.edu
Website

Joe Lachance is an Assistant Professor in the School of Biological Sciences at Georgia Institute of Technology and a member of the Cell and Molecular Biology Research Program at Winship Cancer Institute.

Lachance received his Ph.D. in Genetics from Stony Brook University in Stony Brook, New York. He conducted his postdoctoral studies as a NIH Kirschstein postdoctoral fellow at the University of Pennsylvania.

Lachance's research is in the areas of human evolutionary genomics, population genetics, and health disparities. His lab integrates large genome-scale datasets with evolutionary theory and computer simulations. They have found evidence of ancient introgression in Africa, inferred that the leading edge of the out-of-Africa migration involved an excess of males, discovered that genetic risks of cancer have decreased over evolutionary time, and identified novel targets of positive selection.

Associate Professor
Phone
404-894-0794
Office
EBB 2103
Research Focus Areas
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Lynn Kamerlin

Lynn Kamerlin
skamerlin3@gatech.edu
http://kamerlinlab.com

Lynn Kamerlin received her Master of Natural Sciences from the University of Birmingham (UK), in 2002, where she remained to complete a PhD in Theoretical Organic Chemistry under the supervision of Dr. John Wilkie (awarded 2005). Subsequently, she was a postdoctoral researcher in the labs of Stefan Boresch at the University of Vienna (2005-2007), Arieh Warshel at the University of Southern California (2007-2009, Research Associate at the University of Southern California in 2010) and Researcher with Fahmi Himo (2010). She is currently a Professor and Georgia Research Alliance – Vasser Wooley Chair of Molecular Design at Georgia Tech, a Professor of Structural Biology at Uppsala University, a Fellow of the Royal Society of Chemistry. She has also been a Wallenberg Scholar, the recipient of an ERC Starting Independent Researcher Grant (2012-2017) and the Chair of the Young Academy of Europe (YAE) in 2014-2015. Her non-scientific interests include languages (fluent in 5), amateur photography and playing the piano.

Professor
Fellow of the Royal Society of Chemistry
Phone
(404) 385-6682
Office
MoSE 2120A
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Christopher E. Carr

Christopher E. Carr
cecarr@gatech.edu
Lab Website

Christopher E. Carr is an engineer/scientist with training in aero/astro, electrical engineering, medical physics, and molecular biology. At Georgia Tech he is an Assistant Professor in the Daniel Guggenheim School of Aerospace Engineering with a secondary appointment in the School of Earth and Atmospheric Sciences. He is a member of the Space Systems Design Lab (SSDL) and runs the Planetary eXploration Lab (PXL). He serves as the Principal Investigator (PI) or Science PI for several life detection instrument and/or astrobiology/space biology projects, and is broadly interested in searching for and expanding the presence of life beyond Earth while enabling a sustainable human future. He previously served as a Research Scientist at MIT in the Department of Earth, Atmospheric and Planetary Sciences and a Research Fellow at the Massachusetts General Hospital in the Department of Molecular Biology. He serves as a Scott M. Johnson Fellow in the U.S. Japan Leadership Program.

Assistant Professor
School of Aerospace Engineering
School of Earth and Atmospheric Sciences
Phone
617-216-5012
Office
ESM 107B
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Saurabh Sinha, Ph.D.

Saurabh Sinha, Ph.D.
Lab

Saurabh Sinha received his Ph.D. in Computer Science from the University of Washington, Seattle, in 2002, and after post-doctoral work at the Rockefeller University with Eric Siggia, he joined the faculty of the University of Illinois, Urbana-Champaign, in 2005, where he held the positions of Founder Professor in Computer Science and Director of Computational Genomics in the Carl R. Woese Institute for Genomic Biology until 2022. He joined Georgia Institute of Technology in 2022, as Wallace H. Coulter Distinguished Chair in Biomedical Engineering, with joint appointments in Biomedical Engineering and Industrial & Systems Engineering. Sinha’s research is in the area of bioinformatics, with a focus on regulatory genomics and systems biology. Sinha is an NSF CAREER award recipient and has been funded by NIH, NSF and USDA. He co-directed an NIH BD2K Center of Excellence and was a thrust lead in the NSF AI Institute at UIUC. He led the educational program of the Mayo Clinic-University of Illinois Alliance, and co-led data science education for the Carle Illinois College of Medicine. Sinha has served as Program co-Chair of the annual RECOMB Regulatory and Systems Genomics conference and served on the Board of Directors for the International Society for Computational Biology (2018-2021). He was a recipient of the University Scholar award of the University of Illinois, and selected as a Fellow of the AIMBE in 2018.

Wallace H. Coulter Distinguished Chair in Biomedical Engineering
Professor
Office
3108 UAW
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Eric Gaucher

Eric Gaucher
eric.gaucher@biology.gatech.edu
Website

Gaucher was guided in biochemistry by Peter Tipton and Bayesian Theory by George Smith. Gaucher subsequently earned his Ph.D. from the University of Florida under the tutelage of Steve Benner and Michael Miyamoto.[1] Gaucher received the Walter M. Fitch Award from the Society for Molecular Biology and Evolution for his graduate work.[2] He then did postdoctoral work with NASA's Astrobiology Institute in conjunction with a National Research Council Fellowship. After the two-year fellowship, Gaucher served as President of the Foundation for Applied Molecular Evolution.

Gaucher was hired as an Associate Professor by the Georgia Institute of Technology in 2008 [1][3][4] The Gaucher group conducts basic and applied research at the interface of molecular evolution and synthetic biology. As of February 2016, his h-index, as calculated by Google Scholar, is 25.[5]

Gaucher is also the founder and president of the early-stage biotechnology company General Genomics. His company exploits novel platforms to engineer proteins for the biomedical and industrial sectors.

Adjunct Associate Professor
Phone
404-385-3265
Office
EBB 5013
Additional Research
Our laboratory has diverse research interests including: evolutionary synthetic biology, molecular biology, comparative genomics, computational biology, bioinformatics, biomedicine, molecular evolution and origins of life, and evolution and engineering of protein thermostability.
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http://www.biology.gatech.edu/people/eric-gaucher
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Annalise Paaby

Annalise Paaby
paaby@gatech.edu
Website

After studying ecology as a biology major at Swarthmore College, Annalise Paaby learned fly pushing as a technician for Steve DiNardo and then discovered evolutionary genetics as a tech for Paul Schmidt. She joined Paul’s lab as a graduate student and earned her Ph.D. from the University of Pennsylvania in 2009. In 2015, Paaby completed her postdoctoral training with Matt Rockman at New York University and began her appointment at Georgia Tech.

Assistant Professor
Phone
404-385-4588
Office
EBB 3011
Additional Research
Our lab explores major questions in evolution and quantitative genetics. We work with the nematode wormC. elegansand relatedCaenorhabditisspecies. Current projects include exploring how cryptic alleles in embryogenesis depend on genetic background, how development evolves over time, and the role of molecular mechanisms in trait determination and evolution. We are also interested in how the environment influences trait expression and imposes selection in natural populations, and are conducting field collection trips in the nearby Appalachian foothills.
Research Focus Areas
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Patrick McGrath

Patrick McGrath
patrick.mcgrath@biology.gatech.edu
Website

Patrick McGrath's research group is interested in understanding the genetic basis of heritable behavioral variation. In the current age, it has become cheap and easy to catalog the set of genetic differences between two individuals. But which genetic differences are responsible for generating differences in innate behaviors, including liability to neurological diseases such as autism, bipolar disease, and schizophrenia? How do these causative genetic variants modify a nervous system? Besides their role in disease, genetic variation is the substrate for natural selection. To understand how behavior evolves, we must understand how it varies.

Associate Professor
Phone
404-385-0071
Office
EBB 3013
Additional Research
Mostbiological traits have a strong genetic, or heritable, component. Understanding how genetic variation influences these phenotypes will be important for understanding common, heritable diseases like autism.However, the genetic architecture controlling most biological traits is incredibly complex - hundreds of interacting genes and variants combine in unknown ways to create phenotype.The McGrath lab is interested in using fundamentalmechanistic studies inC. elegansto identify, predict, and understand how genetic variation impacts the function of the nervous system.We are studying laboratory adapted strains and harnessing directed evolution experiments to understand how genetic changes affect development, reproduction, and lifespan. We combine quantitative genetics, CRISPR/Cas9, genomics, and computational approaches to address these questions.We believe this work will lead to insights into evolution, multigenic disease, and systems biology.
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http://biosciences.gatech.edu/people/patrick-mcgrath
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