Vinayak Agarwal

Vinayak Agarwal's profile picture
vagarwal@gatech.edu
Website

Vinny is an Assistant Professor at Georgia Tech with joint appointments at the School of Chemistry and Biochemistry and School of Biological Sciences.

A majority of antibiotics and drugs that we use in the clinic are derived or inspired from small organic molecules called Natural Products that are produced by living organisms such as bacteria and plants. Natural Products are at the forefront of fighting the global epidemic of antibiotic resistant pathogens, and keeping the inventory of clinically applicable pharmaceuticals stocked up. Some Natural Products are also potent human toxins and pollutants, and we need to understand how these toxins are produced to minimize our and the environmental exposure to them.

We as biochemists ask some simple questions- how and why are Natural Products produced in Nature, what we can learn from Natural Product biosynthetic processes, and how we can exploit Nature's synthetic capabilities for interesting applications?

Broadly, we are interested in questions involving (meta)genomics, biochemistry, structural and mechanistic enzymology, mass spectrometry, analytical chemistry, and how natural product chemistry dictates biology.

Assistant Professor
Phone
404-385-3798
Office
Petit Biotechnology Building, Office 3315
Additional Research

A majority of antibiotics and drugs that we use in the clinic are derived or inspired from small organic molecules called Natural Products that are produced by living organisms such as bacteria and plants. Natural Products are at the forefront of fighting the global epidemic of antibiotic resistant pathogens, and keeping the inventory of clinically applicable pharmaceuticals stocked up. Some Natural Products are also potent human toxins and pollutants, and we need to understand how these toxins are produced to minimize our and the environmental exposure to them. We as biochemists ask some simple questions- how and why are Natural Products produced in Nature, what we can learn from Natural Product biosynthetic processes, and how we can exploit Nature's synthetic capabilities for interesting applications? Broadly, we are interested in questions involving (meta)genomics, biochemistry, structural and mechanistic enzymology, mass spectrometry, analytical chemistry, and how natural product chemistry dictates biology.

Related Site

Stefan France

Stefan France's profile picture
stefan.france@chemistry.gatech.edu
Website

Stefan France is an Associate Professor in the School of Chemistry and Biochemistry. Professor France earned his B.S. in Chemistry (2000) from Duke University and a M.A. (2003) and Ph.D. (2005) in Organic Chemistry from Johns Hopkins University. His research group focuses on experimental methodology development, natural product synthesis, and medicinal chemistry. Owing to Prof. France's avid interest in undergraduate research, his research group has mentored and trained more than 60 undergraduates (both Georgia Tech and non-Georgia Tech students). Professor France has been the recipient of several awards for his research, mentorship, and teaching including: the 2018 Georgia Tech-Georgia Power Professor of Excellence; the 2015 Georgia Tech Senior Faculty Outstanding Undergraduate Mentor Award; the 2014 Georgia Tech Faculty Award for Academic Outreach; the 2014 Georgia Tech Hesberg Teaching Award; the 2013 Georgia Tech Sigma Xi Young Faculty Award; the 2012 National Organization for the Professional Advancement for Black Chemists and Chemical Engineers (NOBCChE) Lloyd N. Ferguson Young Scientist Award; and the 2011 National Science Foundation (NSF) CAREER Award. He heads the Chemistry FAST Program, a NSF Research Experiences for Undergraduates (REU) Site, and also serves as Chair of the NSF Chemistry REU Leadership Group.

Associate Professor
Phone
404-385-1796
Office
MoSE 2100K
Additional Research

Our group is interested in the design of efficient methodologies to accomplish the formation of carbon-carbon and carbon-heteroatom bonds with the intent to apply the methodology toward the synthesis of complex natural and unnatural targets. Natural Product Synthesis. Approaches to natural products not only inspire the development of new synthetic strategies, but often unveil unexpected and often interesting reactivity. Targets are chosen for their interesting biological activity along with their sheer complexity. We are interested in exploring both modular and convergent approaches to complex targets that enable facile derivatization for the development of combinatorial libraries. Medicinal Chemistry. Medicinal or pharmaceutical chemistry lies at the intersection of chemistry and pharmacy. Our group is interested in the design, synthesis and development of pharmaceutical drugs, or other chemical entities suitable for therapeutic use. We are further interested in the study of their biological properties and their quantitative structure-activity relationships (QSAR). Given that medicinal chemistry is a highly interdisciplinary science, we aim to establish several collaborations with biologists, biochemists, and computational chemists to facilitate the design and development process. In particular, we aim to develop therapeutics toward the treatment of various forms of cancer, HIV, diabetes, and neurological disorders, such as Alzheimer's and Parkinson's disease.

Google Scholar
https://scholar.google.com/citations?user=UQE3zMQAAAAJ&hl=en&oi=ao
Related Site

Andrew Medford

Andrew Medford's profile picture
andrew.medford@chbe.gatech.edu
Website

Dr. Medford is interested in leveraging materials informatics, statistics, and machine learning to maximize the practical impact of fundamental atomic-scale simulations in the field of surface science and catalysis. His research areas include heterogeneous catalysis, oxide surface chemistry, density functional theory, kinetic models, uncertainty quantification, and Bayesian optimization and inference.

Assistant Professor, School of Chemical and Biomolecular Engineering
Phone
(404) 385-5531
Additional Research

Catalysis, Biochemicals, Biorefining, Chemistry, Sugars, Molecular Simulations, Computational Biology

Valerie Thomas

Valerie Thomas's profile picture
valerie.thomas@isye.gatech.edu
ISyE Profile

Valerie Thomas is the Anderson-Interface Chair of Natural Systems and Professor in the H. Milton School of Industrial and Systems Engineering, with a joint appointment in the School of Public Policy. 

Dr. Thomas's research interests are energy and materials efficiency, sustainability, industrial ecology, technology assessment, international security, and science and technology policy. Current research projects include low carbon transportation fuels, carbon capture, building construction, and electricity system development. Dr. Thomas is a Fellow of the American Association for the Advancement of Science, and of the American Physical Society. She has been an American Physical Society Congressional Science Fellow, a Member of the U.S. EPA Science Advisory Board, and a Member of the USDA/DOE Biomass Research and Development Technical Advisory Committee. 

She has worked at Princeton University in the Princeton Environmental Institute and in the Center for Energy and Environmental Studies, and at Carnegie Mellon University in the Department of Engineering and Public Policy.

Dr. Thomas received a B. A. in physics from Swarthmore College and a Ph.D. in theoretical physics from Cornell University.

Anderson-Interface Chair of Natural Systems
Professor, School of Industrial and Systems Engineering
RBI Initiative Lead: Sustainability Analysis
Phone
(404) 894-0390
Additional Research

Hydrogen Transport/Storage; Biofuels; ClIMaTe/Environment; Electric Vehicles; System Design & Optimization; Energy and Materials Efficiency; Sustainability; Industrial Ecology; Technology Assessment; Science and Technology Policy

Website

Meisha Shofner

Meisha Shofner's profile picture
meisha.shofner@mse.gatech.edu
Shofner Lab

Meisha L. Shofner is a professor in the School of Materials Science and Engineering at Georgia Institute of Technology, joining the faculty following post-doctoral training at Rensselaer Polytechnic Institute. She received her B.S. in Mechanical Engineering from The University of Texas at Austin and her Ph.D. in Materials Science from Rice University. Prior to beginning graduate school, she was employed as a design engineer at FMC in the Subsea Engineering Division, working at two plant locations (Houston, Texas and the Republic of Singapore), and she is a registered Professional Engineer in Georgia.

Shofner’s research area is processing-structure-property relationships of polymers and composites. Specifically, she designs processing strategies to attain hierarchical structures in these materials to improve properties and has discovered scalable processing methods to produce auxetic structures and tensegrity-inspired structures. Additionally, she works with bioderived materials to produce composites with reduced environmental impact.  

Professor, School of Materials Science and Engineering
Phone
404.385.7216
Office
MRDC 4409
Additional Research

Biomolecular-Solids; Biomaterials; Composites; Polymers; Nanomaterials; Biofuels; Structure-property relationships in polymer nanocomposite materials; producing structural hierarchy in these materials for structural and functional applications.

Google Scholar
https://scholar.google.com/citations?hl=en&user=BrXwtO4AAAAJ&view_op=list_works&sortby=pubdate
MSE Profile Page

Kamran Paynabar

Kamran Paynabar's profile picture
kamran.paynabar@isye.gatech.edu
Departmental Bio

Kamran Paynabar is the Fouts Family Early Career Professor and Associate Professor in the H. Milton Stewart School of Industrial and Systems Engineering at Georgia Tech. He received his B.Sc. and M.Sc. in Industrial Engineering from Iran in 2002 and 2004, respectively, and his Ph.D. in Industrial and Operations Engineering from The University of Michigan in 2012. He also holds an M.A. in Statistics from The University of Michigan. His research interests comprise both applied and methodological aspects of machine-learning and statistical modeling integrated with engineering principles. He is a recipient of the INFORMS Data Mining Best Student Paper Award, the Best Application Paper Award from IIE Transactions, the Best QSR refereed paper from INFORMS, and the Best Paper Award from POMS. He has been recognized with the Georgia Tech campus level 2014 CETL/BP Junior Faculty Teaching Excellence Award and the Provost Teaching and Learning Fellowship. He served as the chair of QSR of INFORMS, and the president of QCRE of IISE.

Assistant Professor
Phone
404.385.3141
Office
Groseclose Building, Room 436
Additional Research
  • Aerospace
  • Artificial Intelligence
  • Automotive
  • Big Data Analytics
  • Biobased Materials
Personal Website

Guanghui (George) Lan

 Guanghui (George) Lan's profile picture
george.lan@isye.gatech.edu
Website

George Lan is an A. Russell Chandler III Professor of Industrial and Systems Engineering at Georgia Institute of Technology.  His research and teaching interests lie in theory, algorithms and applications of stochastic optimization and nonlinear programming.  Most of his current research concerns the design of efficient algorithms for solving challenging optimization problems, especially those arising from data analytics, machine learning, and reinforcement learning. He is actively pursuing the applications of these methodologies in healthcare and sustainability areas. Dr. Lan serves as the associate editor for Computational Optimization and Applications (2014 – present), Mathematical Programming (2016 – present) and SIAM Journal on Optimization (2016  – present). Dr. Lan is an associate director for the center of machine learning at Georgia Tech.

Associate Professor
Additional Research

Chromatin; Epigenetics    

Lily Cheung

Lily Cheung's profile picture
lily.cheung@gatech.edu
Website

Lily Cheung got her research start as a sophomore at Rutgers University, where she graduated Summa Cum Laude with a B.S. in Chemical Engineering in 2008. She then earned her Ph.D. in Chemical Engineering from Princeton University in 2013. Under the supervision of Stanislav Shvartsman, she characterized gene regulatory networks controlling the development of the model organism Drosophila melanogaster, using a combination of molecular biology, genetics, and reaction-diffusion modeling.

During her postdoctoral training with Wolf Frommer at the Carnegie Institution for Science, she designed biomolecular sensors to quantify sugar transport in plants. Her current interests include the use of high-throughput quantitative techniques and mathematical modeling to advance our understanding of how metabolic and gene regulatory networks interact to control plant growth.

Lily is the recipient of a NSF NPGI Postdoctoral Fellowship in Biology, a NSF CAREER Award, and a Human Frontier Science Program Early Career Award.

Assistant Professor
Phone
404-894-2826
Office
ES&T L1230
Additional Research

Engineering of genetically encoded biosensors Quantitative fluorescence microscopy and image analysis Computational models of gene regulatory networks Transcriptional regulation and developmental biology of plants The past fifteen years has seen dramatic advancements in genome sequencing and editing. The cost of sequencing a genome has decreased by two orders of magnitude, giving rise to new systems-level approaches to biology research that aim to understand life as an emerging property of all the molecular interactions in an organism. At the same time, technologies that allow site-specific modifications of the genome are enabling researchers to manipulate multicellular organisms in unprecedented ways. From reductionist approaches to systems biology, and from conventional plant breeding to synthetic biology, the future of plant biology research relies on the adoption of computational methods to analyze experimental data and develop predictive models. In biomedicine, mathematical models are already revolutionizing drug discovery; in agriculture, they have the potential to generate more efficient, faster growing crop varieties. The goal of the Cheung lab is to bring quantitative techniques and mathematical modeling to plants in order to gain systems-level insight into their physiology and development - particularly to understanding how metabolic and gene regulatory networks interact to control homeostasis and growth.

Research Focus Areas
Related Site

Karl Jacob

Karl Jacob's profile picture
karl.jacob@mse.gatech.edu

Karl I. Jacob, a professor of Materials Science and Engineering with a joint appointment in the G. W. Woodruff School of Mechanical Engineering, teaches graduate and undergraduate courses on polymer physics and engineering, rheology, and mechanics of polymeric materials. His graduate work was in the area of numerical analysis of vibrating three-dimensional structures. He came to Georgia Tech from DuPont Corporation in 1995. His initial work at the DuPont Dacron Research Laboratory was in the area of fiber-reinforced composite materials and in the development and modeling of fiber spinning processes. He then moved to the DuPont Central Research and Development Department, where he was involved in molecular modeling, computational chemistry, and diffusion.

Jacob is a member of the American Academy of Mechanics, the American Society of Mechanical Engineers, the Sigma Xi Research Society, and the Phi Kappa Phi Honor Society.

Professor, School of Materials Science and Engineering and School of Mechanical Engineering
Phone
404.894.2541
Office
MRDC-1 4509
Additional Research

"Dr. Jacob's research is directed at stress induced phase changes, nanoscale characterization of materials, synthesis of polymeric nanofibers, mechanical behavior of fiber assemblies (particularly related to biological systems and biomimitic systems), nanoparticle reinforced composites, transdermal drug delivery systems, large scale deformation of rubbery (networked) polymers, and nanoscale fracture of materials. The objectives in this work, using theoretical, computational and experimental techniques, is to understand the effect of micro- and nano- structures in the behavior of materials in order to try to design the micro/nano structures for specific materials response. Dr. Jacob plans are to continue current research interests with a multidisciplinary thrust with more emphasis in bio related areas and to start some work on the dynamic behavior of materials and structures. Graduate students could benefit from the interdisciplinary nature of the work combining classical continuum mechanics with nanoscale analysis for various applications, particularly in the nano and bio areas. Dr. Jacob has extensive experience in vibrations and stability of structures, mechanics of polymeric materials, behavior of fiber assemblies, stress-induced phase transformation, diffusion, and molecular modeling. His research involves the application of mechanics principles, both theoretical and experimental, in the analysis and design of materials for various applications.";Fibers; smart textiles; fuel cells; Polymeric composites

University, College, and School/Department
MSE Profile Page

Zhaohui (Julene) Tong

Zhaohui (Julene) Tong's profile picture
zt7@gatech.edu
Website

The Tong Lab tackles challenges in the interdisciplinary areas of bioresource engineering and sustainable chemistry. We develop innovative technologies for producing chemicals, materials, energy, and fuels from renewable resources.

Current research interests include:

  • Functional biomaterials for high-efficiency circular economy
  • Platform chemicals and hydrocarbon fuels from renewable resources
  • Sustainable process control and modeling
  • Nano-biomaterial synthesis and self-assembling
  • Polymer degradation and recycling

Disciplines:

  • Materials and Nanotechnology

  • Energy and Sustainability

Associate Professor, School of Chemical and Biomolecular Engineering
Phone
404.894.3098
Office
ES&T 2226