Research Publications

High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing.

Sago CD, Lokugamage MP, Paunovska K, Vanover DA, Monaco CM, Shah NN, Gamboa Castro M, Anderson SE, Rudoltz TG, Lando GN, Mummilal Tiwari P, Kirschman JL, Willett N, Jang YC, Santangelo PJ, Bryksin AV, Dahlman JE.

Proc Natl Acad Sci U S A. 2018 Oct 16;115(42):E9944-E9952. doi: 10.1073/pnas.1811276115.

Modifying a Commonly Expressed Endocytic Receptor Retargets Nanoparticles in Vivo.

Sago CD, Lokugamage MP, Lando GN, Djeddar N, Shah NN, Syed C, Bryksin AV, Dahlman JE.

Nano Lett. 2018 Sep 20. doi: 10.1021/acs.nanolett.8b03149.

Bacteria-Based Materials for Stem Cell Engineering.

Hay JJ, Rodrigo-Navarro A, Petaroudi M, Bryksin AV, García AJ, Barker TH, Dalby MJ, Salmeron-Sanchez M.

Adv Mater. 2018 Oct;30(43):e1804310. doi: 10.1002/adma.201804310.

Analyzing 2000 in Vivo Drug Delivery Data Points Reveals Cholesterol Structure Impacts Nanoparticle Delivery.

Paunovska K, Gil CJ, Lokugamage MP, Sago CD, Sato M, Lando GN, Gamboa Castro M, Bryksin AV, Dahlman JE.

ACS Nano. 2018 Aug 28;12(8):8341-8349. doi: 10.1021/acsnano.8b03640. 

A Direct Comparison of in Vitro and in Vivo Nucleic Acid Delivery Mediated by Hundreds of Nanoparticles Reveals a Weak Correlation.

Paunovska K, Sago CD, Monaco CM, Hudson WH, Castro MG, Rudoltz TG, Kalathoor S, Vanover DA, Santangelo PJ, Ahmed R, Bryksin AV, Dahlman JE.

Nano Lett. 2018 Mar 14;18(3):2148-2157. doi: 10.1021/acs.nanolett.8b00432.