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“Protein Intrinsic Disorder: Cause and Consequence” 

 
Meeting Agenda
 
Petit Biotechnology Building (IBB),Suddath Seminar Room 1128
Georgia Institute of Technology, 315 Ferst Drive NW, Atlanta, GA
Thursday, February 27, 2025
11:00 - 11:45 a.m. 2025 Suddath Award Presentation
“Enabling Technologies for Next-Generation Cell-Free Diagnostics”
Alexandra Patterson, Ph.D. Candidate, Mark Styczynski, Advisor 
11:45 - 12:00 p.m.Presentation of 2025 Suddath Award Brant and Vincent Suddath
Official Opening of the 2025 Suddath Symposium
 
1:00 p.m. Opening RemarksNick Hud, IBB Associate Director, J.C. Gumbart, Matthew Torres - Symposium Co-Chairs
Session I 
1:05 p.m.'Biophysical Conservation of Intrinsically Disordered Regions" Alex Holehouse, Washington University, St. Louis
1:45 p.m."Conformational Dynamics in Early Protein Evolution" Lynn Kamerlin, Georgia Tech
2:25 p.m.Break 
Session II  
2:45 p.m"From Polyfunctionality to Multipathogenicity with Intrinsic Disorder"Vladimir Uversky, University of South Florida
3:25 p.m."Accessing Phosphorylation-induced Conditional Protein Folds in the Meta-proteome Through Generative Machine Learning”Matthew Torres, Georgia Tech
4:05 p.m."Liquid-liquid Phase Separation, Amyloid Oligomer Formation, and Heterotypic Amyloid" Anant Paravastu, Georgia Tech
4:45 p.mAdjourn 
Friday, February 28, 2025
8:30 a.m.Breakfast, Nerem Atrium 
Session III 
9:10 a.m."Liquid-Liquid Phase Separation and Fibrillization of the Tau Protein" Joan-Emma Shea, University of California, Santa Barbara
9:50 a.m."From Disorder to New Order: IDRs, LLPS and Prions"Yury Chernoff, Georgia Tech
10:30 a.m.Break 
11:00 a.m.“Pathogenic Aggregation of Glaucoma-associated Myocilin” Raquel Lieberman, Georgia Tech
11:40 a.m.Poster Session and Lunch, Nerem Atrium 
Session IV
1:30 p.m"Uncovering Molecular Driving Forces to Macroscopic Properties in Biomolecular Condensates Through Multiscale Computational Models"Jeetain Mittal, Texas A&M University
2:10 p.m."Finding Functional Properties of Complex Condensates at the Synapse"Nathan McDonald, Georgia Tech
2:50 p.m.Break 
3:10 p.m."From Physics to Biology and Back Again: How Physical Understanding of Condensate Properties can Explain Biological Function and Disease Processes"Tanja Mittag, St. Jude Children's Research Hospital
3:50 p.m.“Programmability and High-fidelity Probing of Intracellular Condensates Driven by Disordered Proteins”Felipe Quiroz, Emory University/Georgia Tech
4:30 p.m.Closing Remarks 
4:40 p.m.Adjourn