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Applied Bioinformatics Laboratory
Core Capabilities:
Bioinformatics
Computational genomics
Transcriptomics analysis
Molecular typing
Machine learning
Biostatistical analysis
Contacts: King Jordan, king.Jordan@biology.gatech.edu
Andrew Conley, Andrew.conley@biosci.gatech.edu
Biomechanics Core
Core Capabilities:
Compression testing
Uniaxial tensile testing
Uniaxial Torsion testing
Cyclic fatigue testing
Flexural testing
Contact: Laxmi Krishnan, biomech@gatech.edu
Biomolecular Analysis Core
Core Capabilities:
Laser capture microdissection, Gel, blot and tissue, Imaging, PCR Analysis, Freeze drying, Fluorescence absorbance and luminescence analysis
Contact: Robert Hughley, robert.hughley@ibb.gatech.edu
Biopolymer Characterization Core
Core Capabilities:
HPLC, FPLC, Circular dichroism/fluorescence, Size exclusion chromatography, Multimode DLS, Ultracentrifugation, multimode DSF, Stopped flow, high throughput absorbance/fluorescence /chemiluminescence, ITC, Stop flow kinetics analysis, Analytical ultracentrifugation, Protein stability analysis, High-performance and ultracentrifugation
Contact: Robert Hughley, robert.hughley@ibb.gatech.edu
Cellular Analysis and Cytometry Core
Core Capabilities:
Spectral Flow Cytometry (up to 40 color Fluorescence Detection System), Conventional Flow Cytometry (up to 18 color Fluorescence Detection Systems), Fluorescence Activated Cell Sorting (2-way, 4-way, and Plate with Index Sorting), Imaging Flow Cytometry, Mass Cytometry and Tissue Imaging Mass Cytometry, Particle Sizing and Counting from 0.2um - 1600um, Nanoparticle Counting and Characterization
Contact: ibb-cac@groups.gatech.edu
Genome Analysis Core
Core Capabilities:
qRT-PCR & RT-PCR
Nucleofection
Single cell isoation (large sample number)
Single cell isolation (small sample number)
Digital drop PCR
Contact: Naima Djedder, naima.djeddar@ibb.gatech.edu
High Throughput DNA Core
Core Capabilities:
Rapid runs with and without reagents, High output, TruSEq DNA, Nextera DNA, Nextera XT, TruSEq RNA sequencing, Nextera rapid capture, Nextera library quantification, Tru Seq quantification, NOVA SEQ, Oligonucleotide synthesis
Contact: Shweta Biliya, shweta.biliya@biology.gatech.edu
Histology Core
Core Capabilities:
Paraffin and Resin Automatic & Manual Tissue Processing, Cryogenic, Paraffin & Resin Embedding, Paraffin, Resin and Cryo-Microtomy, Diamond Saw Sectioning, Hematoxylin & Eosin Stain, Special Stains and Immunohistochemistry, Antigen Retrieval, Exakt Grinding System Slides, Histology Consulting & Training, Grossing, Plant Histology, Sample Decalcification, Tissue Fixation, Coverslipping, Protocol Optimization
Contact: Aqua Asberry, aqua16@gatech.edu
Magnetic Resonance Imaging Core
Core Capabilities:
Small Animal MRI, Engineering Applications of MRI, Magnetic Resonance Spectroscopy, flow-MRI, MRI technology
Contact: Johannes Leisen, johannes.leisen@chemistry.gatech.edu
Microcomputed Tomography Core
Core Capabilities:
Sample cT, in vivo cT, 3D reconstruction of cT slices, cT image analysis
Contact: Laxmi Krishnan, microct@gatech.edu
Molecular Evolution Core (Research)
Core Capabilities:
Genome Sequencing, Library preparation/construction, Plasmid sequencing, Sanger sequencing, Next Gen sequencing, RNASeq, Automated sample Handling Automated, Phage Display, Cloning, Fragment Analysis, Yeast Surface Display, Automated Colony picking, Library Screening, gel extraction, Oligonucleotide synthesis, Bacterial Surface Display, Custom ELISA, Error Prone PCR, Bioanalyzer; DNA; RNA; Protein, Electroporation, Custom Selection Systems Design, scFvs, Qiacube DNA; RNA; Protein Purification, Colony Picking, Custom Sequencing Libraries, Competent Bacterial Cells
Contact: Anton Bryksin, anton.bryksin@ibb.gatech.edu
Molecular Evolution Core (CLIA Lab)
Core Capabilities:
Genome Sequencing, Library preparation/construction, Plasmid sequencing, Sanger sequencing, Next Gen sequencing, RNASeq, Automated sample Handling Automated, Phage Display, Cloning, Fragment Analysis, Yeast Surface Display, Automated Colony picking, Library Screening, gel extraction, Oligonucleotide synthesis, Bacterial Surface Display, Custom ELISA, Error Prone PCR, Bioanalyzer; DNA; RNA; Protein, Electroporation, Custom Selection Systems Design, scFvs, Qiacube DNA; RNA; Protein Purification, Colony Picking, Custom Sequencing Libraries, Competent Bacterial Cells
Contact: Anton Bryksin, anton.bryksin@ibb.gatech.edu
Neuro Design Suite
Core Capabilities:
Intracellular single cell electrophysiology recording, Extracellular electrophysiology recording, Microelectrode fabrication, Viral (nano-particle) injection, Cell Cultures
Contact: Bo Yang, bo.yang@me.gatech.edu
Optical Microscopy Core
Core Capabilities:
Laser scanning confocal
Spinning disk confocal
Multi-photon excitation- inverted and upright
Lightsheet
Widefield and Slide/plate scanner
TIRF microscopy
Super resolution SIM
Super resolution- dSTORM and PALM
Swept field Confocal
LaserCapture Microdissection
Contacts: Sandy Hsieh, sandy.hsieh@ibb.gatech.edu
Danielle Scheff, danielle.scheff@ibb.gatech.edu
Systems Mass Spectrometry (Proteomics and Metabolomics)
Core Capabilities:
Discovery and targeted proteomics
Protein identification and quantification
Protein-Protein interaction studies
Posttranslational modification analysis
Intact protein analysis, protein complex characterization
Non-targeted polar and/or non-polar metabolomic assays
Targeted assays
Exact mass measurement
Mass spectrometry imaging
Sample preparation, data collection, data processing, data analysis, annotation, and interpretation
Contact: symsc@ibb.gatech.edu
