For IBB Faculty – Major Equipment in Cores (updated July 2024)

Petit Institute for Bioengineering and Bioscience Core Facilities (by Building) 

Cores in the Petit Biotechnology Building

Microscopy Core

  • Zeiss LSM 780/ ELYRA super resolution microscope system 
  • Zeiss LSM 980 NLO multi-photon excitation confocal microscope system 
  • Zeiss LSM 700 confocal microscope system
  • Zeiss LSM 900 w/ Airy Scan confocal microscope systems (2) 
  • Zeiss PALM Microbeam laser capture micro-dissection system 
  • Molecular Devices ImageXpress PICO high content imaging system 
  • Zeiss AxioObserver Z1 Fluorescence microscope
  • Biotek Cytation 7 Reader/Imager w/ BioSpa 8 Robotic incubator, plate handler, and washer

Biomechanics Core

  • MTS MiniBionix 858 uniaxial servohydraulic material testing system (axial/ torsion)
  • Bose / TA Instruments ElectroForce 3200 Axial Extended Stroke (high displacement) configuration 
  • Bose / TA Instruments ElectroForce 3200 Axial/Torsion configuration
  • Bose / TA Instruments ElectroForce 3100 uniaxial material testing system (small displacement/load) 
  • Anton Parr MCR302 Rheometer

MicroCT Core

  • Scanco Medical micro CT 40 tissue scanner
  • Scanco Medical micro CT 50 high resolution tissue scanner 
  • Scanco Medical viva CT 40 small animal scanner
  • Siemens Inveon CT scanner

High Throughput DNA Sequencing Core

  • Illumina NovaSeq 6000 High throughput DNA sequencing system

Magnetic Resonance Imaging Core

  • Bruker PharmaScan 7T MRI Scanner

  • SAII animal monitoring and gating system

  • Volume and surface coils in various sizes and configurations from Bruker, Doty Scientific and M2M imaging

Histology Core

  • Accu-Scope EXC-350 Brightfield Microscope w/ 4K HDMI Camera
  • Buehler Ecomet 3 Grinder
  • Epredia Autostainer 360 for IHC, IF, and MultiPlex Staining
  • Epredia ClearVue Coverslipper
  • Epredia Cryostar NX-70 Cryostat w/ Vacuum
  • Epredia PT Module for Antigen Retrieval
  • EXAKT Grinding System
  • General Data Paraffin Dispenser PRO
  • General Data TECII 2120 Tissue Embedding System
  • Intelsint RTPH-360 Enclosed Tissue Processor
  • Leica Autostainer XL
  • Leica CM3050S Cryostat
  • Leica VT1000 S Vibratome
  • Lunaphore LabSat Multiplex IHC
  • Metkon Miracut 152 Precision Saw
  • Thermo Scientific Cryostar NX-70 Cryostat
  • VWR 1400E Vacuum Oven
  • Waldorf (Germany) HM355S Microm Rotary Microtome (2)
  • Zeiss 100M Fluorescence Microscope w/ Camera

Biomolecular Analysis Core

  • Beckman Coulter Analytical HPLC
  • LiCor Biosciences Odyssey CLX infrared imager 
  • Agilent Bioanalyzer DNA, RNA and Protein Analysis
  • Labconco Centivap Concentrator/Cold Trap speed vac system (2)
  • Labconco FreeZone 6 Freeze Drying System (2) 
  • Revity Tri-Carb LSC 4910TR scintillation counter
  • Amaxa Nucleofector cell electroporator
  • Perkin Elmer IVIS Spectrum CT in vivo imaging system 
  • Applied Biosystems Step One Plus sequence detector 
  • Beckman Allegra R15 benchtop centrifuge
  • Optima Max XP benchtop ultra centrifuge
  • Packard Cobra II auto-gamma counter, 
  • Beckman Coulter XPN 100 ultracentrifuge 
  • Avanti J1-30I high speed centrifuge
  • Fast Prep Tissue Homogenizer
  • Biotek Synergy H4 multi-mode plate reader (2) 
  • GE FLA 9500 Imager
  • GE AI 600 RGB Imager

Cellular Analysis and Cytometry Core

  • Amnis Imagestream X imaging flow cytometer
  • Fluidigm Helios Platform Mass cytometer and Hyperion imaging mass cytometer 
  • BD S8 cell sorter
  • BD Melody Cell sorter w/ VBR lasers
  • Beckman Coulter CytoFLEX S flow cytometer w/ plate loader 
  • Cytek Aurora full spectrum cytometer w/ automated sample loader
  • IZON Exoid Tunable Resistive Pulse Sensing (TRPS) instrument 
  • Beckman Coulter Multisizer 4e cell counter
  • NucleCounter NC-202 
  • LiCor DLx Gel Imager

Systems Mass Spectrometry Core

  • Vanquish Horizon LC / ThermoFisher Scientific Q Exactive HF MS 
  • Vanquish Horizon LC / ThermoFisher Scientific Orbitrap ID-X MS 
  • Vanquish Horizon LC / ThermoFisher Scientific Exploris 240 MS (2)
  • Bruker Amazon Speed Ion Trap with ETD
  • Bruker rapiFlex MALDI TOF
  • ThermoFisher Scientific GC / ISQ 7610 MS 
  • ThermoFisher Scientific Dionex Ultimate 3000 RSLC

Microcomputed Tomography Core

  • MicroCT40 Small specimen scanner (Scanco)
  • MicroCT50 Small specimen scanner (Scanco)
  • VivaCT40 In vivo specimen scanner (Scanco)
  • Inveon In vivo specimen scanner (Siemens)

Neuro Design Suite

  • Axon MultiClamp 700B Amplifier 
  • Slice Scope Pro 1000
  • Slice Scope Pro 3000
  • Digidata 1550A Digitizer
  • TDT 128 Channel Neurophysiology System
  • P-340 fura2
  • Sutter P-2000

 

Cores in the Engineered Biosystems Building 

Microscopy Core

  • Perkin Elmer Spinning Disk System
  • Zeiss Z1 Dual Illumination Light Sheet Fluorescence Microscope System
  • Zeiss Lattice SIM 3
  • Nikon CSU-W1 Spinning Disk Confocal System
  • Bruker Opterra II Swept Field Microscope System Bruker Vutara 352 Super Resolution Microscope System
  • Bruker Investigator Upright Multi-photon excitation System

Cellular Analysis and Cytometry Core

  • BD FACSAria Fusion 
  • BD LSR Fortessa
  • BD Melody Cell sorter (B/YG/R lasers)
  • Isoplexsis IsoLight single cell proteomics analyzer
  • Axion Biosystems Maestro Pro multi-well microelectrode array (MEA) and impedance system 
  • Cytek Aurora full spectrum cytometer w/ automated sample loader
  • Beckman Coulter CytoFLEX S flow cytometer w/ plate loader

Genome Analysis Core 

  • Bio Rad QX200 ddPCR
  • Qiagen QIAcuity digital PCR system
  • Lonza 4D Nucleofector Core Unit 10X Genomics Chromium X System 
  • BioRad ddSEQ single cell isolator
  • Bionano Genomics Saphyr genome imaging system

Biopolymer Characterization Core 

  • BioTek Synergy H4 Microplate Readers 
  • AP Chirascan™-plus CD Spectrometer
  • Olis RSM1000 Stopped-Flow Spectrophotometer
  • Shimadzu NEXERA with RI, Fluorescence and PDA detector 
  • Wyatt DynaPro NanoStar Dynamic Light Scattering
  • GE AKTAPure 25M with refrigerator
  • GE Ultrospec 2100 pro UV-Vis Spectrometer 
  • OmniSEC REVEAL
  • OnmiSEC
  • Malvern Zeta-sizer (zeta potential measurement) 
  • Beckman XPN ultracentrifuge
  • Beckman Avanti centrifuge
  • Wyatt Dynapro plate reader (DLS with HTS capacity)
  • Prometheus nanoDSF (native differential scanning fluorimeter) 
  • Nanotemper technologies 
  • MicroCal VP-DSC 2M (Differential scanning calorimeter)
  • MicroCal iTC200 (Isothermal calorimetry)
  • Beckman Optima AUC + Schlieren optics (analytical ultracentrifugation)

Molecular Evolution Core (Research)

  • ABI Step One Plus real time PCR system
  • Electrophoresis equipment
  • New Brunswick Scientific Innova 44 Shaker 
  • NuAire NU 475-500
  • Illumina MiSeq system
  • Illumina iSEQ system 
  • Illumina NextSeq 500
  • Illumina MiniSeq
  • Oxford Nanopore MinION
  • Grenova Tip Washer 
  • BIOSETT ASM 2000 DNA oligo synthesizer 
  • Qiagen Qiacube Connect nucleic acid extraction system
  • Tissuelyser II sample disruptor
  • Agilent Tapestation
  • Agilent Bioanalyzer 2100
  • Sage Science Blue Pippin automated gel extraction system
  • Covaris R230 focused ultrasonicator
  • ThermoFisher Scientific SeqStudio Sanger sequencing system
  • ThermoFisher Scientific SeqStudio Flex Sanger sequencing system
  • Beckman Coulter Echo 525 acoustic liquid handling system 
  • Crocodile ELISA Robot 
  • Qpix 2XT Colony picker
  • Andrew Alliance Liquid Handling System 
  • Stratagene Mx3005P qPCR System 
  • DXS Automated ELISA System 
  • Taspestri Single cell Multi-omics system

Molecular Evolution Core (CLIA Lab)

  • BSC LYSIS Hood
  • Traceable® Ultra-Low Temperature WIFI Data Logger with TraceableLIVE® Cloud Service Pipette Communication Module
  • Integra Assist PLUS liquid handling system 
  • BMG Labtech CLARIOstar Plus plate reader 
  • California Air Compressor
  • KingFisher Flex nucleic acid extraction system
  • Thermo Scientific Quantstudio 5 real time PCR system
  • Thermo Scientific Quantstudio 6 Flex real time PCR system
  • SPT Labtech XL-100 automated liquid handling system
  • Formulatrix Mantis liquid handling system
  • Omni bead ruptors

Systems Mass Spectrometry Core

  • Dionex UltiMate 3000 RSLCnano UHPLC system / ThermoFisher Scientific QE Plus MS (2)
  • Waters Acquity I Class LC
  • Beckman PF-2D Chromatography system
  • VanquishNeo LC/ThermoFisher Scientific Exploris480

 

Cores in Molecular Science and Engineering Building

Systems Mass Spectrometry Core

  • Bruker Solarix 12T FTICR