Rudolph Gleason

Rudolph Gleason
rudy.gleason@me.gatech.edu

Rudolph (Rudy) L. Gleason began at Tech in Fall 2005 as an assistant professor. Prior, he was a postdoctoral fellow at Texas A&M University. He is currently a professor in the School of Mechanical Engineering and the School of Biomedical Engineering in the College of Engineering. Gleason’s research program has two key and distinct research aims. The first research aim is to quantify the link between biomechanics, mechanobiology, and tissue growth and remodeling in diseases of the vasculature and other soft tissues. The second research aim is to translate engineering innovation to combat global health disparities and foster sustainable development in low-resource settings around the world. Gleason serves as a Georgia Tech Institute for People and Technology initiative lead for research activities related to global health and well-being.

Professor, Mechanical Engineering and Biomedical Engineering
Joint Appointment in the School of Biomedical Engineering
Phone
404-385-7218
Office
TEP 205
Additional Research

Cardiovascular mechanics, soft tissue growth and remodeling, and tissue engineering

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https://scholar.google.com/scholar?hl=en&as_sdt=0,11&q=rl+gleason+jr&oq=RL+Gleason
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Stephen Sprigle

Stephen Sprigle
stephen.sprigle@design.gatech.edu
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Stephen Sprigle is a Professor at the Georgia Institute of Technology with appointments in Bioengineering, Industrial Design and the George W. Woodruff School of Mechanical Engineering. 

A biomedical engineer with a license in physical therapy, Sprigle directs the Rehabilitation Engineering and Applied Research Lab (REARLab), which focuses on applied disability research and development. The REARLab’s research interests include the biomechanics of wheelchair seating and posture, pressure ulcer prevention, and manual wheelchair propulsion. Its development activities include standardized wheelchair and cushion testing and the design of assistive and diagnostic technologies. Sprigle teaches design-related classes in both the Schools of Industrial Design and Mechanical Engineering.

Professor
Phone
404-385-4302
Office
Architecture 0155
Additional Research
Applied research and device development targeting the increased heath and function of persons with disabilities. Specific areas of interest include: wheeled mobility and seating, pressure ulcer prevention and treatment; design of diagnostic tissue interrogation devices; design of assistive technology. Wheeled Mobility and Seating; Pressure Ulcer Prevention and Treatment; Design of Diagnostic Tissue Interrogation Devices; Design of Assistive Technologies
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David Ku

David Ku
david.ku@me.gatech.edu
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Selected recent publications:

➤ Robert G. Mannino, Eric J. Nehl, Sarah Farmer, Amanda Foster Peagler, Maren C. Parsell, Viviana Claveria, David Ku, David S. Gottfried, Hang Chen, Wilbur A. Lam, and Oliver Brand, “The critical role of engineering in the rapid development of COVID-19 diagnostics: Lessons from the RADx Tech Test Verification Core” Science Advances. 9, eade4962 (2023). https://www.science.org/doi/10.1126/sciadv.ade4962

➤ Liu ZL, Bresette C, Aidun CK, Ku DN. (2021) SIPA in 10 milliseconds: VWF tentacles agglomerate and capture platelets under high shear. Blood Advances doi.org/10.1182/bloodadvances.2021005692

➤ Kim DJ, Ku DN. “Structure of shear-induced platelet aggregated clot formed in an in vitro arterial thrombosis model” Blood Adv (2022) 6 (9): 2872–2883. doi.org/10.1182/bloodadvances.2021006248

➤ Kim DJ, Bressette C, Liu Z, Ku DN. Occlusive thrombosis in arteries.  APL Bioengineering  2019;3, 041502. https://doi.org/10.1063/1.5115554

Licensed Patents

➤ Ku, D.N., Wootton, D.M., Greer-Braddon, L., “Poly(vinyl Alcohol) Cryogel,” No. 5,981,826 and 6,231,605, issued May 15, 2001. Licensed; created prosthetic cartilage; acquired by Wright Medical. $645 million

➤ Denoziere, G., Ku, D.N., “Methods of Producing PVA Hydrogel Implants and Related Devices,” issued U.S. Patent No. 8,038,920, Licensed to Mimedx.  Market cap >$600 million.

Regents Professor
Lawrence P. Huang Chair in Engineering and Entrepreneurship
Executive Director, Atlantic Pediatric Device Consortium
Phone
404-894-6827
Office
Petit Biotechnology Building, Office 2307
Additional Research
New Project: Lysis of platelet clots to treat heart attacksBackground: Heart attacks and strokes come from a sudden thrombosis or accumulation of platelets in an artery.Our Findings: Our group has discovered the biophysical reason for this sudden occlusion and multiple points of therapy to prevent or dissolve the platelet-rich clot. Current Objectives: Quantify the architecture and strength of the thrombus to prevent or dissolve the thrombus using nano-devices and synthetic proteins.
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