Jeannette Yen

Jeannette Yen
jeannette.yen@biology.gatech.edu
School of Biological Sciences Profile Page
Professor, School of Biological Sciences
Phone
404.385.1596
Office
Cherry Emerson A116
Additional Research

Aquatic chemical communicationHydrodynamicsSmall-Scale Biological-Chemical-Physical Interactions in Marine Zooplankton 

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Aquatic Chemical Ecology Lab
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Younan Xia

Younan Xia
younan.xia@bme.gatech.edu
ChBE Profile Page

Xia is the Brock Family Chair and Georgia Research Alliance (GRA) Eminent Scholar in Nanomedicine in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Institute of Technology and Emory University, with joint appointments in School of Chemistry and Biochemistry, and School of Chemical and Biomolecular Engineering. Professor Xia received his Ph.D. degree in Physical Chemistry from Harvard University (with Professor George M. Whitesides) in 1996, his M.S. degree in Inorganic Chemistry from University of Pennsylvania (with the late Professor Alan G. MacDiarmid, a Nobel Laureate in Chemistry, 2000) in 1993, and his B.S. degree in Chemical Physics from the University of Science and Technology of China (USTC) in 1987. He came to the United States of America in 1991. Xia has received a number of prestigious awards, including the 2013 Nano Today Award, the ACS National Award in the Chemistry of Materials (2013), Fred Kavli Distinguished Lecture in Nanoscience at the MRS Spring Meeting (2013), AIMBE Fellow (2011), MRS Fellow (2009 ), NIH Director's Pioneer Award (2006), ACS Leo Hendrik Baekeland Award (2005), Camille Dreyfus Teacher Scholar (2002), David and Lucile Packard Fellowship in Science and Engineering (2000), Alfred P. Sloan Research Fellow (2000), NSF Early Career Development Award (2000), ACS Victor K. LaMer Award (1999), and Camille and Henry Dreyfus New Faculty Award (1997). Xia has been an Associate Editor of Nano Letters since 2002, and has served on the Advisory Boards of Particle & Particle Systems Characterization (2013-), Chemical Physics Letters (2013-), Chemistry: A European Journal (2013-), Chinese Journal of Chemistry (2013-), Angewandte Chemie International Edition (2011-), Advanced Healthcare Materials (2011-, inaugural chairman of the advisory board), Accounts of Chemical Research (2010-), Cancer Nanotechnology (2010-), Chemistry: An Asian Journal (2010-), Journal of Biomedical Optics (2010-), Nano Research (2009-), Science of Advanced Materials (2009-), Nano Today (2006-), Chemistry of Materials (2005-2007), Langmuir (2005-2010, 2013-2015), International Journal of Nanotechnology (2004-), and Advanced Functional Materials (2001-). He has also served as a Guest Editor of special issues for Advanced Materials (six times), Advanced Functional Materials (one time), MRS Bulletin (one time), and Accounts of Chemical Research (one time).

GRA Eminent Scholar in Nanomedicine, Wallace H. Coulter Department of Biomedical Engineering
Professor, Wallace H. Coulter Department of Biomedical Engineering
Brock Family Chair, Wallace H. Coulter Department of Biomedical Engineering
Professor, School of Chemistry and Biochemistry, and School of Chemical and Biomolecular Engineering
Phone
404.385.3209
Office
MSE 3100J
Additional Research
Catalysis; Nanomedicine; Bio-Inspired Materials; Tissue Engineering
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Nanocages Lab
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Vladimir Tsukruk

Vladimir Tsukruk
vladimir@mse.gatech.edu
SEMA Lab

Vladimir V. Tsukruk is a Dean’s Distinguished Professor of Engineering at the School of Materials Science and Engineering, Georgia Institute of Technology, a founding Director of Microanalysis Center, and founding co-director of DoD BIONIC Center of Excellence.  He received MS degree in physics from the National University of Ukraine, PhD in polymer science and DSc in chemistry from the National Academy of Sciences of Ukraine. He carried out his post-doc research at the U. Marburg, Darmstadt TU, and U. Akron.

He serves on the Editorial Advisory Boards of ten professional journals and as an Associate Editor at ACS Applied Materials and Interfaces. He has co-authored more than 400 refereed articles in archival journals and five books, which have been cited more than 15,500 times with H-index of 60 (WoS).  He has organized ten professional symposia and trained about 70 students currently employed in industry, academia, and national labs.  His research in the field of surfaces, interfaces, directed assembly of synthetic/natural polymers and nanostructures, and bioinspired hybrid nanomaterials has been recognized by The Georgia Tech Outstanding Research Author Award (2015), the Humboldt Lectureship (2011), Humboldt Research Award (2010) and the National Science Foundation Special Creativity Award (2006) among others.

Regents' Professor, School of Materials Science and Engineering
Phone
404.894.6081
Office
M Building 3100M
Additional Research

Bio-Inspired Materials; Surfaces and Interfaces; Biomolecular-Solids; Optical Materials; Smart materials. Bionanocomposites, hybrid nanomaterials, optically active materials, photonic materials, responsive materials, and sensors.

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Matthew Torres

Matthew Torres
matthew.torres@biology.gatech.edu
Website

Matt is a former Tar Heel from UNC Chapel Hill. His training is in mass spectrometry-based proteomics and G protein signaling. He has been investigating PTMs since 2001. He is also a co-director of the Systems Mass Spectrometry Core (SYMS-C) facility at Georgia Tech.

Associate Professor
Phone
404-385-0401
Office
EBB 4009
Additional Research
Bioinformatics. My lab integrates mass spectrometry and experimental cell biology using the yeast model system to understand how networks of coordinated PTMs modulate biological function. Now well into the era of genomics and proteomics, it is widely appreciated that understanding individual genes or proteins, although necessary, is often not sufficient to explain the complex behavior observed in living organisms. Indeed, placing context on the dynamic network of relationships that exist between multiple proteins is now one of the greatest challenges in Biology. Post-translational modifications (PTMs, e.g. phosphorylation, ubiquitination and over 200 others), which can be readily quantified by mass spectrometry (MS), often mediate these dynamic relationships through enhancement or disruption of binding and/or catalytic properties that can result in changes in protein specificity, stability, or cellular localization. We use a combination of tools including quantitative mass spectrometry, yeast genetics, dose-response assays, in vitro biochemistry, and microscopy to explore testable systems-level hypotheses. My current research interests can be grouped into four main categories:(1)coordinated PTM-based regulation of dynamic signaling complexes, (2) cross-pathway coordination by PTMs, (3) PTM networks in stress adaptation, and (4) technology development for rapid PTM network detection.
Research Focus Areas
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http://biosciences.gatech.edu/people/matthew-torres
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Todd Sulchek

Todd Sulchek
todd.sulchek@me.gatech.edu
Sulchek Lab

Todd Sulchek is an associate professor in Mechanical Engineering at Georgia Tech where he conducts fundamental and applied research in the field of biophysics. His research program focuses on the mechanical and adhesive properties of cell and biological systems and the development of microsystems to aid in their study. His research employs tools, including, MEMS, microfluidics, imaging, and patterning to understand or enable biological systems. His interests include cancer diagnostics, stem cell biomanufacturing, novel therapeutics, and ultracheap engineering tools. He is a member of the interdisciplinary Institute for Bioengineering and Bioscience. Dr. Sulchek also holds program faculty positions in Bioengineering and Biomedical Engineering and has a courtesy appointment in the School of Biology. He received his Ph.D. from Stanford in Applied Physics under Calvin Quate and received a bachelors in math and physics from Johns Hopkins. He was a postdoc and staff scientist at Lawrence Livermore National Lab. He joined Georgia Tech in 2008 as an Assistant Professor of Mechanical Engineering. He is a recipient of the NSF CAREER award, the BP Junior Faculty Teaching Excellence Award, the Lockheed Inspirational Young Faculty award, and the 2012 Petit Institute Above and Beyond Award. To date he has published 42 journal papers and has filed or been issued 7 patents. Prof. Sulchek is a strong supporter of undergraduate research, and he participates in a variety of undergraduate education activities including the Undergraduate Research Opportunities Program (UROP) and includes over 8 undergraduate authors in the past year.

Professor, Woodruff School of Mechanical Engineering
Appointments in Bioengineering, Biomedical Engineering, and Biology
Phone
404.385.1887
Office
Petit 2309
Additional Research

Biomedical Devices; bio-MEMS; biosensors; Drug Delivery; Advanced Characterization. Dr. Sulchek's research focuses primarily on the measurement and prediction of how multiple individual biological bonds produce a coordinated function within molecular and cellular systems. There are two complementary goals. The first is to understand the kinetics of multivalent pharmaceuticals during their targeting of disease markers; the second is to quantify the host cell signal transduction resulting from pathogen invasion. Several tools are developed and employed to accomplish these goals. The primary platform for study is the atomic force microscope (AFM), which controls the 3-D positioning of biologically functionalized micro- and nanoscale mechanical probes. Interactions between biological molecules are quantified in a technique called force spectroscopy. Membrane protein solubilized nanolipoprotein particles (NLPs) are also used to functionalize micro/nano-scale probes with relevant biological mediators. This scientific program requires the development of enabling instrumentation and techniques, which include the following: Advanced microscopy and MEMs; Nanomechanical linkers, which provide a convenient platform to control biomolecular interactions and study multivalent molecular kinetics; Biological mimetics, which provide a simple system to study cell membranes and pathogens. UltIMaTely, this work is used to optimize molecular drug targeting, improve chem/bio sensors, and develop more efficient pathogen countermeasures.

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Stephen Sprigle

Stephen Sprigle
stephen.sprigle@design.gatech.edu
Website

Stephen Sprigle is a Professor at the Georgia Institute of Technology with appointments in Bioengineering, Industrial Design and the George W. Woodruff School of Mechanical Engineering. 

A biomedical engineer with a license in physical therapy, Sprigle directs the Rehabilitation Engineering and Applied Research Lab (REARLab), which focuses on applied disability research and development. The REARLab’s research interests include the biomechanics of wheelchair seating and posture, pressure ulcer prevention, and manual wheelchair propulsion. Its development activities include standardized wheelchair and cushion testing and the design of assistive and diagnostic technologies. Sprigle teaches design-related classes in both the Schools of Industrial Design and Mechanical Engineering.

Professor
Phone
404-385-4302
Office
Architecture 0155
Additional Research
Applied research and device development targeting the increased heath and function of persons with disabilities. Specific areas of interest include: wheeled mobility and seating, pressure ulcer prevention and treatment; design of diagnostic tissue interrogation devices; design of assistive technology. Wheeled Mobility and Seating; Pressure Ulcer Prevention and Treatment; Design of Diagnostic Tissue Interrogation Devices; Design of Assistive Technologies
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Minoru Shinohara

Minoru  Shinohara
shinohara@gatech.edu
Departmental Profile Page

Physiological and biomechanical mechanisms underlying fine motor skills and their adjustments and adaptations to heightened sympathetic nerve activity, aging or inactivity, space flight or microgravity, neuromuscular fatigue, divided attention, and practice in humans. He uses state-of-the-art techniques in neuroscience, physiology, and biomechanics (e.g., TMS, EEG, fMRI, single motor unit recordings, microneurography, mechanomyography, ultrasound elastography, and exoskeleton robot) in identifying these mechanisms.

Associate Professor; School of Biological Sciences
Phone
404.894.1030
Office
555 14th St | Suite 1309C
Additional Research

Neuromuscular Physiology

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LinkedIn Human Neuromuscular Physiology Lab
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Krishnendu Roy

Krishnendu Roy
krish.roy@gatech.edu
https://engineering.vanderbilt.edu/bio/krishnendu-roy

 In August 2023, Krishnendu Roy joined Vanderbilt University as the Bruce and Bridgitt Evans Dean of Engineering and a University Distinguished Professor in Biomedical Engineering, and Pathology, Microbiology, and Immunology, with a secondary appointment in Chemical and Biomolecular Engineering.

Previously, Roy served as Robert A. Milton Endowed Chair for the Coulter Department of Biomedical Engineering at Georgia Tech. He is also the former Director of the NSF Engineering Research Center (ERC) for Cell Manufacturing Technologies (CMaT), Center for ImmunoEngineering at Georgia Tech, and Marcus Center for Therapeutic Cell Characterization and Manufacturing. 

His overall research interests are in developing novel concepts for stem cell engineering as well as polymer controlled delivery of biological factors, especially for nucleic acid therapeutics (DNA, SiRNA and oligos) and immunoengineering. Currently, his group is involved in the following major areas of research; (a) Developing novel concepts to produce biodegradable surface functionalized micro-and nanoparticles for targeted and sustained delivery of nucleic acids, proteins, peptides and other immune modulators. In particular he is interested in developing multi-agent vaccine delivery systems for cancer and infectious diseases as well as immunotherapies for autoimmune diseases. (b) Creating spatio-temporally patterned polymer scaffolds for directed compartmental differentiation of stem cells into multiple lineages. (c) Engineering an artificial thymic niche for directed differentiation of stem cells into functional, antigen- specific T cells. (e) The development of novel nanoimprinting techniques to generate shape specific, environmentally triggered drug nanocarriers.

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Bruce and Bridgitt Evans Dean of Engineering at Vanderbilt University
University Distinguished Professor
Professor of Biomedical Engineering
Professor of Pathology, Microbiology and Immunology
Professor of Chemical and Biomolecular Engineering
Phone
404.385.6166
Additional Research
The overall goal of our research endeavor is the development of new biomaterial-based strategies for gene/drug delivery and stem cell engineering. Towards this, my laboratory focuses on three major directions: (a) design and development of novel delivery systems for nucleic-acid based immunotherapy and cancer chemotherapy (b) engineering complex microenvironments to study and manipulate stem cells and understand their behavior in biomimetic, three-dimensional conditions and (c) developing novel engineering tools and high throughput methods to generate functional T cells and Dendritic cells from stem cells.
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H. Jerry Qi

H. Jerry Qi
qih@me.gatech.edu
Active Materials & Additive Manufacturing Lab

H. Jerry Qi is a professor and the Woodruff Faculty Fellow in the George W. Woodruff School of Mechanical Engineering at Georgia Institute of Technology. He received his bachelor degrees (dual degree), master and Ph.D. degree from Tsinghua University (Beijing, China) and a ScD degree from Massachusetts Institute of Technology (Boston, MA, USA). After one year postdoc at MIT, he joined University of Colorado Boulder as an assistant professor in 2004, and was promoted to associate professor with tenure in 2010. He joined Georgia Tech in 2014 as an associate professor with tenure and was promoted to a full professor in 2016. Qi is a recipient of NSF CAREER award (2007). He is a member of Board of Directors for the Society of Engineering Science. In 2015, he was elected to an ASME Fellow. The research in Qi's group is in the general area of soft active materials, with a focus on 1) 3D printing of soft active materials to enable 4D printing methods; and 2) recycling of thermosetting polymers. The material systems include: shape memory polymers, light activated polymers, vitrimers. On 3D printing, they developed a wide spectrum of 3D printing capability, including: multIMaTerial inkjet 3D printing, digit light process (DLP) 3D printing, direct ink write (DIW) 3D printing, and fused deposition modeling (FDM) 3D printing. These printers allow his group to develop new 3D printing materials to meet the different challenging requirements. For thermosetting polymer recycling, his group developed methods that allow 100% recycling carbon fiber reinforced composites and electronic packaging materials. Although his group develops different novel applications, his work also relies on the understanding and modeling of material structure and properties under environmental stimuli, such as temperature, light, etc, and during material processing, such as 3D printing. Constitutive model developments are typically based on the observations from experiments and are then integrated with finite element through user material subroutines so that these models can be used to solve complicated 3D multiphysics problems involving nonlinear mechanics. A notable example is their recent pioneer work on 4D printing, where soft active materials is integrated with 3D printing to enable shape change (or time in shape forming process). Recently, his developed a state-of-the-art hybrid 3D printing station, which allows his group to integrate different polymers and conduct inks into one system. Currently, his group is working on using this printing station for a variety of applications, including printed 3D electronics, printed soft robots, etc.

Professor, Woodruff School of Mechanical Engineering
Woodruff Faculty Fellow, Woodruff School of Mechanical Engineering
Phone
404.385.2457
Office
MRDC 4104
Additional Research

Additive/Advanced Manufacturing; micro and nanomechanics; Recycling; Soft Materials; Conducting Polymers

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Mark Prausnitz

Mark Prausnitz
mark.prausnitz@chbe.gatech.edu
Center for Drug Design, Development and Delivery

Professor Mark R. Prausnitz is a Regents' Professor and the Love Family Professor in Chemical and Bimolecular Engineering in the School of Chemical & Bimolecular Engineering. He received his B.S. in 1988 from Stanford University and his Ph.D. in 1994 from the Massachusetts Institute of Technology. Professor Prausnitz and his colleagues carry out research on biophysical methods of drug delivery, which employ microneedles, ultrasound, lasers, electric fields, heat, convective forces and other physical means to control the transport of drugs, proteins, genes and vaccines into and within the body. A major area of focus involves the use of microneedle patches to apply vaccines to the skin in a painless, minimally invasive manner. In collaboration with Emory University, the Centers for Disease Control and Prevention, and other organizations, Professor Prausnitz's group is advancing microneedles from device design and fabrication through pharmaceutical formulation and pre-clinical animal studies through studies in human subjects. In addition to developing a self-administered influenza vaccine using microneedles, Professor Prausnitz is translating microneedle technology especially to make vaccination in developing countries more effective. The Prausnitz group has also developed hollow microneedles for injection into the skin and into the eye in collaboration with Emory University. In the skin, research focuses on insulin administration to human diabetic patients to increase onset of action by targeting insulin delivery to the skin. In the eye, hollow microneedles enable precise targeting of injection to the suprachoroidal space and other intraocular tissues for minimally invasive delivery to treat macular degeneration and other retinal diseases. Professor Prausnitz and colleagues also study novel mechanisms to deliver proteins, DNA and other molecules into cells. Cavitation bubble activity generated by ultrasound and by laser-excitation of carbon nanoparticles breaks open a small section of the cell membrane and thereby enables entry of molecules, which is useful for gene-based therapies and targeted drug delivery. In addition to research activities, Professor Prausnitz teaches an introductory course on engineering calculations, as well as two advanced courses on pharmaceuticals and technical communication, both of which he developed. He also serves the broader scientific and business communities as a frequent consultant, advisory board member and expert witness.

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Regents' Professor, School of Chemical and Bimolecular Engineering
J. Erskine Love Jr. Chair; Chemical and Biomolecular Engineering
Director, Center for Drug Design, Development and Delivery
Phone
404.894.5135
Office
Petit 1312
Additional Research
Micro and Nano Engineering; Nanomedicine; microneedle patches; Microfabrication; nanoparticle drug delivery
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