Hicham Drissi

Hicham Drissi
hicham.drissi@emory.edu

Hicham Drissi is a professor in the Department of Orthopaedics at Emory University School of Medicine. He holds a Ph.D. from Paris Descartes University.

Professor
Professor, Department of Orthopaedics
Vice Chairman, Research, Department of Orthopaedics
Office
Emory Orthopaedic and Spine Research Room 2000
Additional Research
Identifying molecular and developmental cues that govern skeletal tissue derived cell growth and differentiation.
University, College, and School/Department
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Cheng Zhu

Cheng Zhu
cheng.zhu@bme.gatech.edu
Cellular and Molecular Biomechanics Laboratory

Our interests lie in the adhesion and signaling molecules of the immune system as well as those involved in platelet adhesion and aggregation. We are primarily focused on early cell surface interaction kinetics and their primary signaling responses, as these are critical in determining how a cell will ultimately respond upon contact with another cell. The majority of our work ranges from single molecule interaction studies using atomic force microscopy, molecular dynamics simulations, or biomembrane force probe assays to single cell studies using micropipette adhesions assays, fluorescence imaging techniques, or real-time confocal microscopy. These assays focus on the mechanics and kinetics of receptor-ligand binding and their downstream signaling effects within cells. T cell receptors, selectins, integrins, and their respective ligands are some of the cell surface molecules currently under investigation in our lab. Understanding the initial interaction between molecules such as these and their subsequent early signaling processes is crucial to elucidating the response mechanisms of these physiological systems. Ultimately, our research strives to help better understand the mechanisms within these systems for possible medical applications in autoimmunity, allergy, transplant rejection, and thrombotic disorders. 

Regents' Professor, Coulter Department of Biomedical Engineering
J. Erskine Love Jr. Endowed Chair, Coulter Department of Biomedical Engineering
Executive Director, International Programs, Coulter Department of Biomedical Engineering
Phone
404.894.3269
Office
UAW 1210
Additional Research

BioinformaticsBiomechanicsCell biophysicsElectron MicroscopyMechanobiology

Google Scholar
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Aaron Young

Aaron Young
aaron.young@me.gatech.edu
Exoskeleton and Prosthetic Intelligent Controls (EPIC) Lab

Aaron Young is an Associate Professor in Mechanical Engineering and is interested in designing and improving powered orthotic and prosthetic control systems for persons with stroke, neurological injury or amputation. His previous experience includes a post-doctoral fellowship at the University of Michigan in the Human Neuromechanics Lab working with exoskeletons and powered orthoses to augment human performance. He has also worked on the control of upper and lower limb prostheses at the Center for Bionic Medicine (CBM) at the Rehabilitation Institute of Chicago. His master's work at CBM focused on the use of pattern recognition systems using myoelectric (EMG) signals to control upper limb prostheses. His dissertation work at CBM focused on sensory fusion of mechanical and EMG signals to enable an intent recognition system for powered lower limb prostheses for use by persons with a transfemoral amputation.

Associate Professor, George W. Woodruff School of Mechanical Engineering
Director, EPIC Lab
Phone
404.385.5306
Office
GTMI 433
Additional Research

Powered prosthesis; EMG signal processing. Young's research is focused on developing control systems to improve prosthetic and orthotic systems. His research is aimed at developing clinically translatable research that can be deployed on research and commercial systems in the near future. Some of the interesting research questions are how to successfully extract user intent from human subjects and how to use these signals to allow for accurate intent identification. Once the user intent is identified, smart control systems are needed to maximally enable individuals to accomplish useful tasks. For lower limb devices, these tasks might include standing from a seated position, walking, or climbing a stair. We hope to improve clinically relevant measures with powered mechatronic devices, including reducing metabolic cost, improving biomechanics and decreasing the time required to perform daily tasks of living.

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Jeannette Yen

Jeannette Yen
jeannette.yen@biology.gatech.edu
School of Biological Sciences Profile Page
Professor, School of Biological Sciences
Phone
404.385.1596
Office
Cherry Emerson A116
Additional Research

Aquatic chemical communicationHydrodynamicsSmall-Scale Biological-Chemical-Physical Interactions in Marine Zooplankton 

Google Scholar
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Aquatic Chemical Ecology Lab
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Younan Xia

Younan Xia
younan.xia@bme.gatech.edu
ChBE Profile Page

Xia is the Brock Family Chair and Georgia Research Alliance (GRA) Eminent Scholar in Nanomedicine in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Institute of Technology and Emory University, with joint appointments in School of Chemistry and Biochemistry, and School of Chemical and Biomolecular Engineering. Professor Xia received his Ph.D. degree in Physical Chemistry from Harvard University (with Professor George M. Whitesides) in 1996, his M.S. degree in Inorganic Chemistry from University of Pennsylvania (with the late Professor Alan G. MacDiarmid, a Nobel Laureate in Chemistry, 2000) in 1993, and his B.S. degree in Chemical Physics from the University of Science and Technology of China (USTC) in 1987. He came to the United States of America in 1991. Xia has received a number of prestigious awards, including the 2013 Nano Today Award, the ACS National Award in the Chemistry of Materials (2013), Fred Kavli Distinguished Lecture in Nanoscience at the MRS Spring Meeting (2013), AIMBE Fellow (2011), MRS Fellow (2009 ), NIH Director's Pioneer Award (2006), ACS Leo Hendrik Baekeland Award (2005), Camille Dreyfus Teacher Scholar (2002), David and Lucile Packard Fellowship in Science and Engineering (2000), Alfred P. Sloan Research Fellow (2000), NSF Early Career Development Award (2000), ACS Victor K. LaMer Award (1999), and Camille and Henry Dreyfus New Faculty Award (1997). Xia has been an Associate Editor of Nano Letters since 2002, and has served on the Advisory Boards of Particle & Particle Systems Characterization (2013-), Chemical Physics Letters (2013-), Chemistry: A European Journal (2013-), Chinese Journal of Chemistry (2013-), Angewandte Chemie International Edition (2011-), Advanced Healthcare Materials (2011-, inaugural chairman of the advisory board), Accounts of Chemical Research (2010-), Cancer Nanotechnology (2010-), Chemistry: An Asian Journal (2010-), Journal of Biomedical Optics (2010-), Nano Research (2009-), Science of Advanced Materials (2009-), Nano Today (2006-), Chemistry of Materials (2005-2007), Langmuir (2005-2010, 2013-2015), International Journal of Nanotechnology (2004-), and Advanced Functional Materials (2001-). He has also served as a Guest Editor of special issues for Advanced Materials (six times), Advanced Functional Materials (one time), MRS Bulletin (one time), and Accounts of Chemical Research (one time).

GRA Eminent Scholar in Nanomedicine, Wallace H. Coulter Department of Biomedical Engineering
Professor, Wallace H. Coulter Department of Biomedical Engineering
Brock Family Chair, Wallace H. Coulter Department of Biomedical Engineering
Professor, School of Chemistry and Biochemistry, and School of Chemical and Biomolecular Engineering
Phone
404.385.3209
Office
MSE 3100J
Additional Research
Catalysis; Nanomedicine; Bio-Inspired Materials; Tissue Engineering
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Vladimir Tsukruk

Vladimir Tsukruk
vladimir@mse.gatech.edu
SEMA Lab

Vladimir V. Tsukruk is a Dean’s Distinguished Professor of Engineering at the School of Materials Science and Engineering, Georgia Institute of Technology, a founding Director of Microanalysis Center, and founding co-director of DoD BIONIC Center of Excellence.  He received MS degree in physics from the National University of Ukraine, PhD in polymer science and DSc in chemistry from the National Academy of Sciences of Ukraine. He carried out his post-doc research at the U. Marburg, Darmstadt TU, and U. Akron.

He serves on the Editorial Advisory Boards of ten professional journals and as an Associate Editor at ACS Applied Materials and Interfaces. He has co-authored more than 400 refereed articles in archival journals and five books, which have been cited more than 15,500 times with H-index of 60 (WoS).  He has organized ten professional symposia and trained about 70 students currently employed in industry, academia, and national labs.  His research in the field of surfaces, interfaces, directed assembly of synthetic/natural polymers and nanostructures, and bioinspired hybrid nanomaterials has been recognized by The Georgia Tech Outstanding Research Author Award (2015), the Humboldt Lectureship (2011), Humboldt Research Award (2010) and the National Science Foundation Special Creativity Award (2006) among others.

Regents' Professor, School of Materials Science and Engineering
Phone
404.894.6081
Office
M Building 3100M
Additional Research

Bio-Inspired Materials; Surfaces and Interfaces; Biomolecular-Solids; Optical Materials; Smart materials. Bionanocomposites, hybrid nanomaterials, optically active materials, photonic materials, responsive materials, and sensors.

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Matthew Torres

Matthew Torres
matthew.torres@biology.gatech.edu
Website

Matt is a former Tar Heel from UNC Chapel Hill. His training is in mass spectrometry-based proteomics and G protein signaling. He has been investigating PTMs since 2001. He is also a co-director of the Systems Mass Spectrometry Core (SYMS-C) facility at Georgia Tech.

Associate Professor
Phone
404-385-0401
Office
EBB 4009
Additional Research
Bioinformatics. My lab integrates mass spectrometry and experimental cell biology using the yeast model system to understand how networks of coordinated PTMs modulate biological function. Now well into the era of genomics and proteomics, it is widely appreciated that understanding individual genes or proteins, although necessary, is often not sufficient to explain the complex behavior observed in living organisms. Indeed, placing context on the dynamic network of relationships that exist between multiple proteins is now one of the greatest challenges in Biology. Post-translational modifications (PTMs, e.g. phosphorylation, ubiquitination and over 200 others), which can be readily quantified by mass spectrometry (MS), often mediate these dynamic relationships through enhancement or disruption of binding and/or catalytic properties that can result in changes in protein specificity, stability, or cellular localization. We use a combination of tools including quantitative mass spectrometry, yeast genetics, dose-response assays, in vitro biochemistry, and microscopy to explore testable systems-level hypotheses. My current research interests can be grouped into four main categories:(1)coordinated PTM-based regulation of dynamic signaling complexes, (2) cross-pathway coordination by PTMs, (3) PTM networks in stress adaptation, and (4) technology development for rapid PTM network detection.
Research Focus Areas
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Todd Sulchek

Todd Sulchek
todd.sulchek@me.gatech.edu
Sulchek Lab

Todd Sulchek is an associate professor in Mechanical Engineering at Georgia Tech where he conducts fundamental and applied research in the field of biophysics. His research program focuses on the mechanical and adhesive properties of cell and biological systems and the development of microsystems to aid in their study. His research employs tools, including, MEMS, microfluidics, imaging, and patterning to understand or enable biological systems. His interests include cancer diagnostics, stem cell biomanufacturing, novel therapeutics, and ultracheap engineering tools. He is a member of the interdisciplinary Institute for Bioengineering and Bioscience. Dr. Sulchek also holds program faculty positions in Bioengineering and Biomedical Engineering and has a courtesy appointment in the School of Biology. He received his Ph.D. from Stanford in Applied Physics under Calvin Quate and received a bachelors in math and physics from Johns Hopkins. He was a postdoc and staff scientist at Lawrence Livermore National Lab. He joined Georgia Tech in 2008 as an Assistant Professor of Mechanical Engineering. He is a recipient of the NSF CAREER award, the BP Junior Faculty Teaching Excellence Award, the Lockheed Inspirational Young Faculty award, and the 2012 Petit Institute Above and Beyond Award. To date he has published 42 journal papers and has filed or been issued 7 patents. Prof. Sulchek is a strong supporter of undergraduate research, and he participates in a variety of undergraduate education activities including the Undergraduate Research Opportunities Program (UROP) and includes over 8 undergraduate authors in the past year.

Professor, Woodruff School of Mechanical Engineering
Appointments in Bioengineering, Biomedical Engineering, and Biology
Phone
404.385.1887
Office
Petit 2309
Additional Research

Biomedical Devices; bio-MEMS; biosensors; Drug Delivery; Advanced Characterization. Dr. Sulchek's research focuses primarily on the measurement and prediction of how multiple individual biological bonds produce a coordinated function within molecular and cellular systems. There are two complementary goals. The first is to understand the kinetics of multivalent pharmaceuticals during their targeting of disease markers; the second is to quantify the host cell signal transduction resulting from pathogen invasion. Several tools are developed and employed to accomplish these goals. The primary platform for study is the atomic force microscope (AFM), which controls the 3-D positioning of biologically functionalized micro- and nanoscale mechanical probes. Interactions between biological molecules are quantified in a technique called force spectroscopy. Membrane protein solubilized nanolipoprotein particles (NLPs) are also used to functionalize micro/nano-scale probes with relevant biological mediators. This scientific program requires the development of enabling instrumentation and techniques, which include the following: Advanced microscopy and MEMs; Nanomechanical linkers, which provide a convenient platform to control biomolecular interactions and study multivalent molecular kinetics; Biological mimetics, which provide a simple system to study cell membranes and pathogens. UltIMaTely, this work is used to optimize molecular drug targeting, improve chem/bio sensors, and develop more efficient pathogen countermeasures.

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Stephen Sprigle

Stephen Sprigle
stephen.sprigle@design.gatech.edu
Website

Stephen Sprigle is a Professor at the Georgia Institute of Technology with appointments in Bioengineering, Industrial Design and the George W. Woodruff School of Mechanical Engineering. 

A biomedical engineer with a license in physical therapy, Sprigle directs the Rehabilitation Engineering and Applied Research Lab (REARLab), which focuses on applied disability research and development. The REARLab’s research interests include the biomechanics of wheelchair seating and posture, pressure ulcer prevention, and manual wheelchair propulsion. Its development activities include standardized wheelchair and cushion testing and the design of assistive and diagnostic technologies. Sprigle teaches design-related classes in both the Schools of Industrial Design and Mechanical Engineering.

Professor
Phone
404-385-4302
Office
Architecture 0155
Additional Research
Applied research and device development targeting the increased heath and function of persons with disabilities. Specific areas of interest include: wheeled mobility and seating, pressure ulcer prevention and treatment; design of diagnostic tissue interrogation devices; design of assistive technology. Wheeled Mobility and Seating; Pressure Ulcer Prevention and Treatment; Design of Diagnostic Tissue Interrogation Devices; Design of Assistive Technologies
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Minoru Shinohara

Minoru  Shinohara
shinohara@gatech.edu
Departmental Profile Page

Physiological and biomechanical mechanisms underlying fine motor skills and their adjustments and adaptations to heightened sympathetic nerve activity, aging or inactivity, space flight or microgravity, neuromuscular fatigue, divided attention, and practice in humans. He uses state-of-the-art techniques in neuroscience, physiology, and biomechanics (e.g., TMS, EEG, fMRI, single motor unit recordings, microneurography, mechanomyography, ultrasound elastography, and exoskeleton robot) in identifying these mechanisms.

Associate Professor; School of Biological Sciences
Phone
404.894.1030
Office
555 14th St | Suite 1309C
Additional Research

Neuromuscular Physiology

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