My lab is focused on understanding how proteins and other biological systems function at a molecular level. To probe these systems, we carry out molecular dynamics simulations, modeling biological behavior one atom at a time. The simulations serve as a "computational microscope" that permits glimpses into a cell's inner workings through the application of advanced software and high-powered supercomputers. We are particularly interested in how bacteria utilize unique pathways to synthesize proteins and insert them into both the inner and outer membranes, how they import nutrients across two membranes, and how their cell walls provide shape and mechanical strength.

Melissa Lambeth Kemp received her B.S. in Nuclear Engineering from MIT and her Ph.D. in Bioengineering from University of Washington. Dr. Kemp joined the faculty at Georgia Tech in 2006 after completing postdoctoral training at MIT. Her expertise is in computational modeling of metabolism and signal transduction, as well as developing statistical modeling tools to examine network relationships in high-dimension datasets. One major aspect of her research program linking ROS – the byproducts of aerobic metabolism – to the fundamental way that cells interpret instructions from their environment, their neighbors, and their own genetic blueprint. Specific applications of her diverse work include systems modeling of transient phosphatase oxidation of kinase cascades, patient-specific differences in cytotoxicity to redox-cycled chemotherapeutics and radiation, and the coordination of oxidative metabolism with epithelial-to-mesenchymal transition. Her research program also includes a component of developing high-throughput screening methods for assaying cue-signal-response relationships in cells and analytical tools for single cell gene expression. 

Dr. Kemp currently serves as the Research Director of the multi-site NSF Engineering Research Center “Cell Manufacturing Technologies”. In her former role as Associate Director of the NSF Science and Technology Center “Emergent Behavior of Integrated Cellular Systems”, she spearheaded the multi-site center’s computational activities by developing agent-based models of context-dependent cellular decisions to generate new hypotheses of intercellular communication in pluripotent stem cell differentiation and emergent patterning; this work continues currently in quantifying organizational principles and spatial relationships in iPSC-derived tissues from multi-omics data. Dr. Kemp’s career honors include a Whitaker Graduate Fellowship, Merck/CSBi postdoctoral fellowship, Georgia Cancer Coalition Distinguished Scholar, NIH New Innovator Award, and the CSB2 Prize for Innovative Measurement Methods from the Council for Systems Biology in Boston.

Dr. Kostas Konstantinidis joined the Georgia Institute of Technology as an Assistant Professor in November 2007. He received his BS in Agriculture Sciences from the Aristotle University of Thessaloniki (Greece) in 1999. He continued his studies at the Center for Microbial Ecology at Michigan State University (East Lansing, MI) under the supervision of Prof. James M. Tiedje, where he obtained a PhD in 2004. His PhD studies were fully supported by the Bouyoukos Fellowship program and were devoted in advancing our understanding of the ecology and physiology of soil bacteria through the comparative analysis of their whole-genome sequences. This research resulted in a NSF-funded project to advance the species definition for prokaryotes, which also fostered a short post-doc position at the Center for Microbial Ecology. He then moved to MIT and the laboratory of Prof. Edward DeLong to get trained on innovating metagenomic techniques. His work at MIT provided important new insights into the complexity and function of oceanic microbial communities as well as how life is adapting in the deep and cold Oceans. His research interests are at the interface of genomics and computational biology in the context of microbial ecology with the overarching goal to broaden understanding of the genetic and metabolic potential of the microbial world. Advancing our knowledge on these issues is essential for a better understanding of the microbes that power, by and large, the biogeochemical cycles that sustain life on Earth and cause or control important diseases in humans and animals. He is a member of the American Society for Microbiology (ASM), the International Society for Microbial Ecology (ISME) and the Association of Environmental Engineering and Science Professors (AEESP). Konstantinidis held the Carlton S. Wilder Junior Professorship for five years and subsequently received the Maulding Faculty Fellowship in the School of Civil and Environmental Engineering.

Christine Heitsch is Professor of Mathematics at Georgia Tech, with courtesy appointments in Biological Sciences and Computational Science & Engineering as well as an affiliation with the Petit Institute for Bioengineering & Bioscience.

She is also Director of the new Southeast Center for Mathematics and Biology (SCMB), an NSF-Simons MathBioSys Research Center, and finishing her tenure directing the GT Interdisciplinary Mathematics Preparation and Career Training (IMPACT) Postdoctoral Program.

Heitsch's research interests lie at the interface between discrete mathematics and molecular biology, specifically combinatorial problems "as motivated by" and "with applications to" fundamental biomedical questions like RNA folding.

Students interested in pursuing graduate studies in discrete mathematical biology can do so through a number of GT PhD programs including Bioinformatics or Quantitative Biosciences as well as Algorithms, Combinatorics, and Optimization (ACO), Computational Science & Engineering (CSE), and (of course) Mathematics.
 

Munmun De Choudhury is an Associate Professor at the School of Interactive Computing in Georgia Institute of Technology. Dr. De Choudhury is renowned for her groundbreaking contributions to the fields of computational social science, human-computer interaction, and digital mental health. Through fostering interdisciplinary collaborations across academia, industry, and public health sectors, Dr. De Choudhury and her collaborators have contributed significantly to advancing the development of computational techniques for early detection and intervention in mental health, as well as in unpacking how social media use benefits or harms mental well-being. De Choudhury's contributions have been recognized worldwide, with significant scholarly impact evidenced by numerous awards like induction into the SIGCHI Academy and the 2023 SIGCHI Societal Impact Award. Beyond her academic achievements, Dr. De Choudhury is a proactive community leader, a persistent contributor to policy-framing and advocacy initiatives, and is frequently sought for expert advice to governments, and national and international media.

Dyer’s research interests lie at the intersection of machine learning, optimization, and neuroscience. Her lab develops computational methods for discovering principles that govern the organization and structure of the brain, as well as methods for integrating multi-modal datasets to reveal the link between neural structure and function.

My research focuses on three major areas: (a) understanding and improving worker well-being, (b) temporal dynamics in team contexts, and (c) research methods. Collectively, my research seeks to improve our understanding of optimal human functioning more generally, across time, and within specific contexts (e.g., organizational, teams).

Professor AlRegib is currently a professor in the School of Electrical and Computer Engineering at the Georgia Institute of Technology. He is the director of the Multimedia and Sensors Lab (MSL) at Georgia Tech. In 2012, he was named the director of Georgia Tech’s Center for Energy and Geo Processing (CeGP). He is a faculty member of the Center for Signal and Information Processing (CSIP). He also serves as the director of Georgia Tech’s initiatives and programs in MENA. He has authored and co-authored more than 170 articles in international journals and conference proceedings. He has been issued several U.S. patents and invention disclosures. He is a Senior Member of the IEEE.

Professor AlRegib received the ECE Outstanding Graduate Teaching Award in 2001 and both the CSIP Research and the CSIP Service Awards in 2003. In 2008, he received the ECE Outstanding Junior Faculty Member Award. In 2017, he received the 2017 Denning Faculty Award for Global Engagement.

Professor AlRegib has participated in many service activities. He is an area chair for ICME 2016/17 and the tutorial chair for ICIP 2016. He is a voted member of the IEEE SPS Technical Committees on Multimedia Signal Processing (MMSP) and Image, Video, and Multidimensional Signal Processing (IVMSP). He was a member of the editorial board of the Wireless Networks Journal (WiNET), 2009-2016 and the IEEE Transaction on Circuits and Systems for Video Technology (CSVT), 2014-2016. Currently, he is a member of the the editorial board of the Elsevier journal Signal Processing: Image Communications, 2015-present. He served as the chair of the Special Sessions Program at ICIP’06; the area editor for Columns and Forums in the IEEE Signal Processing Magazine (SPM), 2009–12; the associate editor for IEEE SPM, 2007-09; the tutorials co-chair in ICIP’09; a guest editor for IEEE J-STSP, 2012; a track chair in ICME’11; the co-chair of the IEEE MMTC Interest Group on 3D Rendering, Processing, and Communications, 2010-12; the chair of the Speech and Video Processing Track at Asilomar 2012; and the technical program co-chair of IEEE GlobalSIP, 2014. He is leading a team that is organizing the IEEE VIP Cup, 2017.

His research group, which consists of more than 20 students and researchers, is working on projects related to machine learning, image and video processing, image and video understanding, seismic imaging, perception in visual data processing, healthcare intelligence, and video analytics.

Professor AlRegib has provided services and consultation to several firms, companies, and international educational and R&D organizations. He has been a expert witness in a number of patent infringement cases.

Ashok Goel is a Professor of Computer Science in the School of Interactive Computing at Georgia Institute of Technology in Atlanta, USA. He obtained his Ph.D. from The Ohio State University. At Georgia Tech, he is also the Director of the Ph.D. Program in Human-Centered Computing, a Co-Director of the Center for Biologically Inspired Design, and a Fellow of Brook Byers Institute for Sustainable Systems. For more than thirty years, Ashok has conducted research into artificial intelligence, cognitive science and human-centered computing, with a focus on computational design, modeling and creativity. His recent work has explored design thinking, analogical thinking and systems thinking in biological inspired design (https://www.youtube.com/watch?v=wiRDQ4hr9i8), and his research is now developing virtual research assistants for modeling biological systems. Ashok teaches a popular course on knowledge-based AI as part of Georgia Tech's program on Online Masters of Science in Computer Science. He has pioneered the development of virtual teaching assistants, such as Jill Watson, for answering questions in online discussion forums (https://www.youtube.com/watch?v=WbCguICyfTA). Chronicle of Higher Education recently called virtual assistants exemplified by Jill Watson as one of the most transformative educational technologies in the digital era. Ashok is the Editor-in-Chief of AAAI's AI Magazine.