Throughout my career, my laboratory has studied sphingolipids, a category of lipids that are important in cell structure, signal transduction and cell-cell communication. For more information about what we found, please refer to the Google Scholar or PubMed links below. 

As an Emeritus Professor, I am working on a project that has interested me for a long time--the fact that the active agent in the venom of the brown recluse spider is a sphingomyelinase D that produces a novel product, ceramide 1,3-cyclic phosphate. This activity has also been found in other spiders, bacteria and fungi. With the help of collaborators, I hope to learn more about the organisms that produce and degrade this novel sphingolipid, and possibly find ways to reduce the injury caused by the enzyme when humans encounter it in the environment.

Dr. Lewis A. Wheaton received his Ph.D. in Neuroscience and Cognitive Sciences from the University of Maryland, College Park in 2005. He was a fellow at the National Institutes of Health (Medical Neurology Branch, 2001-2005) studying neural function and recovery of motor control after stroke. In mid-2005 he was awarded a post-doctoral fellowship at the Baltimore Veterans Affairs Medical Center (Maryland) where he performed neuroscience research in aging and stroke motor control in Veterans.

In 2008, Dr. Wheaton joined the School of Applied Physiology at Georgia Tech as an Assistant Professor. He became tenured in 2014 and is currently an Associate Professor in Biological Sciences. Dr. Wheaton is the Director of the Cognitive Motor Control Laboratory at Georgia Tech, engaged in over $1 million in state and federal research funding focused on understanding aspects of human motor control rehabilitation in aging, stroke and amputation. His lab has employed numerous high school, undergraduate, graduate, and post-doctoral fellows. He is the course director for 4 courses in the School of Biological Sciences (Human Neuroimaging, Movement Disorders, Human Neuroanatomy, and the History of Neuroscience). He has Chaired/Co-Chaired 3 international conferences focused on motor control research and clinical outcomes, obtaining funding by federal and private sources. His research has yielded several manuscript publications in the field of motor control neuroscience, several focused expert reviews, and numerous conference presentations both in the US and abroad.

Dr. Wheaton is also an adjunct Associate Professor in the Department of Rehabilitation at Emory School of Medicine and a Member of the Children’s Center for Neurosciences Research at the Emory Children’s Pediatric Research Center.

Dr. Wheaton earned a BS (Biology) degree at Radford University (VA). He is an active parent volunteer at his children's schools and in the local community.

During his graduate work at UC, Berkeley, Simon sought to uncover general principles of animal locomotion that reveal control strategies underlying the remarkable stability and maneuverability of movement in nature. His work has demonstrated the importance animals’ natural dynamics for maintaining stability in the absence of neural feedback. His research emphasizes the importance of placing neural control in the appropriate dynamical context using mathematical and physical models. He has collaborated with researchers at four other institutions to transfer these principles to the design of the next generation of bio-inspired legged robots. 

Simon received his Ph.D. in Integrative Biology at UC, Berkeley and has been a Hertz Fellow since 2002. His work has led to fellowships and awards from the National Science Foundation, the University of California, the Woods Hole Marine Biological Institute, the American Physical Society, the Society of Integrative and Comparative Biology, and the International Association of Physics Students. He is also currently affiliated the new Center for Interdisciplinary Bio-Inspiration in Education and Research (CIBER) at Berkeley.

Dr. Kostas Konstantinidis joined the Georgia Institute of Technology as an Assistant Professor in November 2007. He received his BS in Agriculture Sciences from the Aristotle University of Thessaloniki (Greece) in 1999. He continued his studies at the Center for Microbial Ecology at Michigan State University (East Lansing, MI) under the supervision of Prof. James M. Tiedje, where he obtained a PhD in 2004. His PhD studies were fully supported by the Bouyoukos Fellowship program and were devoted in advancing our understanding of the ecology and physiology of soil bacteria through the comparative analysis of their whole-genome sequences. This research resulted in a NSF-funded project to advance the species definition for prokaryotes, which also fostered a short post-doc position at the Center for Microbial Ecology. He then moved to MIT and the laboratory of Prof. Edward DeLong to get trained on innovating metagenomic techniques. His work at MIT provided important new insights into the complexity and function of oceanic microbial communities as well as how life is adapting in the deep and cold Oceans. His research interests are at the interface of genomics and computational biology in the context of microbial ecology with the overarching goal to broaden understanding of the genetic and metabolic potential of the microbial world. Advancing our knowledge on these issues is essential for a better understanding of the microbes that power, by and large, the biogeochemical cycles that sustain life on Earth and cause or control important diseases in humans and animals. He is a member of the American Society for Microbiology (ASM), the International Society for Microbial Ecology (ISME) and the Association of Environmental Engineering and Science Professors (AEESP). Konstantinidis held the Carlton S. Wilder Junior Professorship for five years and subsequently received the Maulding Faculty Fellowship in the School of Civil and Environmental Engineering.

Raquel Lieberman is the Sepcic-Pfeil Professor of Chemistry & Biochemistry at Georgia Tech. Her research program focuses on biophysical and structural characterization of proteins and the impact of disease-associated mutations on function or dysfunction (e.g. aggregation). Rooted in basic research, the long-term goal of her research program is to convert mechanistic discoveries into disease-modifying therapies.

A major research project in her lab is investigations of glaucoma-associated herocilin, which has been funded by NIH since March 2011. Her lab has made major strides toward detailed molecular understanding of herocilin structure, function, and disease pathogenesis. They have divulged similarities between herocilin-associated glaucoma and other protein misfolding disorders, particularly aherloid diseases. Cumulatively, their work is leading to the first disease-modifying glaucoma therapeutic.

Lieberman also has a track record in membrane enzymes dating back to her thesis work where she solved the first crystal structure of the copper-dependent particulate methane monooxygenase. During her postdoc she shifted focus to intramembrane aspartyl proteases (IAPs), particularly those involved in neurodegenerative disease like Alzheimer’s disease. In her independent lab she developed new proteomics-based assays to measure IAP proteolysis. The lab also collaborates with physicists at Oak Ridge National Labs to use neutron scattering to probe structure and lipids in solution. This work has been funded by NSF and NIH.

She serves on the Executive Council of the Protein Society and as an academic editor for PLoS Biology. She also serves as co-PI of the Department of Education GAANN program in Biochemistry & Biophysics at Georgia Tech and on the advisory committees in a variety of capacities.

Marcus T Cicerone received his Ph.D. from the University of Wisconsin – Madison in 1994, under the direction of Mark Ediger. He spent three years at Johnson & Johnson Clinical Diagnostics, served as a visiting teaching professor at Brigham Young University for two years, and subsequently joined the National Institute of Standards and Technology in 2001, where he remained for 18 years, serving as a group leader and project leader. In January 2019 he joined the Georgia Institute of Technology as a Professor of Chemistry. 

Professor Cicerone is a fellow of American Physical Society, and has received several awards for his efforts in coherent Raman-based biological imaging and for his work in dynamics of liquids and amorphous solids. These include a Johnson & Johnson Director’s Research Award, two Department of Commerce Bronze metals, the 2015 Washington Academy of Sciences Physical & Biological Sciences Award, and the 2017 Arthur S. Flemming Award.

Nian Liu began as an Assistant Professor at Georgia Institute of Technology, School of Chemical and Biomolecular Engineering in January 2017. He received his B.S. in 2009 from Fudan University (China), and Ph.D. in 2014 from Stanford University, where he worked with Prof. Yi Cui on the structure design for Si anodes for high-energy Li-ion batteries. In 2014-2016, he worked with Prof. Steven Chu at Stanford University as a postdoc, where he developed in situ optical microscopy to probe beam-sensitive battery reactions. Dr. Liu 's lab at Georgia Tech is broadly interested in the combination of nanomaterials, electrochemistry, and light microscopy for understanding and addressing the global energy challenges. Dr. Liu is the recipient of the Electrochemical Society (ECS) Daniel Cubicciotti Award (2014) and American Chemical Society (ACS) Division of Inorganic Chemistry Young Investigator Award (2015).

Shaheen Azim Dewji, Ph.D., (she/her/hers) is an Assistant Professor in the Nuclear & Radiological Engineering and Medical Physics Programs at the Georgia Institute of Technology, where she leads the Radiological Engineering, Detection, and Dosimetry (RED²) research group. Dewji joined Georgia Tech following three years as faculty at Texas A&M University in the Department of Nuclear Engineering, and as a Faculty Fellow of the Center for Nuclear Security Science and Policy Initiatives (NSSPI). In her prior role at Oak Ridge National Laboratory, where she remained for almost 9 years, Dewji was Radiological Scientist in the Center for Radiation Protection Knowledge. Her research interests include development of dose coefficients, shielding design, and nuclear material detection assay using gamma-ray spectroscopy. Her recent work has focused on associated challenges in uncertainty quantification in dose estimation/reconstruction associated with the external exposure and internal uptake of radionuclides associated with applications of emergency response, defense, nuclear medicine, and occupational/public safety using Monte Carlo radiation transport codes and internal dose modeling. Dewji completed her Masters and Ph.D. degrees in Nuclear and Radiological Engineering at the Georgia Institute of Technology in Atlanta, GA and was a fellow of the Sam Nunn Security Program. She received her Bachelor of Science in Physics from the University of British Columbia. Dewji currently serves on the National Academies of Science, Engineering, and Medicine – Nuclear and Radiation Studies Board and is a member of the Board of Directors for both the American Nuclear Society and Health Physics Society.
   

Yue Chen is an assistant professor in the Department of Biomedical Engineering, GT/Emory. He received his Ph.D. degree in Mechanical Engineering from Vanderbilt University, M.S. in Mechanical Engineering from Hong Kong Polytechnic University, and a B.S. in Vehicle Engineering from Hunan University. His research focused on designing, modeling, and control of continuum robots and apply them in medicine.