Advancing Neonatal Health Monitoring in Ethiopia
Dec 08, 2025 — Atlanta, GA
Wearable chest-mounted patch and forehead-mounted pulse oximeter shown on a mannequin baby for illustration
Soft, wearable system offers continuous wireless monitoring of newborns’ health.
A new, soft, all-in-one, wearable system has been designed for continuous wireless monitoring of neonatal health in low-resource settings. Developed by Georgia Tech researchers using advanced packaging technologies, the system features a chest-mounted patch and a forehead-mounted pulse oximeter that transmits real-time data to a smartphone app.
The wearable device measures and records important clinical parameters such as heart rate, respiration rate, temperature, electrocardiograms, and blood oxygen saturation. Speedy detection of abnormal readings in resource-challenged neonatal units could significantly reduce newborn mortality rates.
The device’s pilot study, conducted at Tikur Anbessa Specialized Hospital (TASH) in Addis Ababa, in collaboration with Abebaw Fekadu, Ph.D., from the Centre for Innovative Drug Development and Therapeutic Trials for Africa (CDT Africa Inc.), and neonatologist Asrat Demtse, M.D., from the TASH department of pediatrics, demonstrated a significant improvement over current vital sign monitoring and recording methods by providing continuous oversight using less medical equipment while also reducing handwritten paper tracking. Vital signs are a group of the most crucial medical data that indicate the status of the body's life-sustaining functions. The pairing of this wearable system with a smartphone app automated the monitoring process and delivered a superior level of neonatal care compared to the current processes at Ethiopia’s best hospital.
Medical staff and parents also observed a reduced need to wake their babies when using the wearable monitoring system. In addition, after participating in the study, 84% of Ethiopian parents said they would use the device at home.
“Professor Hong Yeo and I connected immediately after he gave a brief research talk about a new, wearable cardiac monitor for children,” said Rudy Gleason. “I asked him if we could co-develop a wearable device for newborn babies in Ethiopia that measured not one, but a variety of vital signs. We both thought it was a great idea.”
Yeo and Gleason are faculty members in the George W. Woodruff School of Mechanical Engineering and the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech. And both are affiliated with Georgia Tech’s Institute for People and Technology, which seeks to improve global health.
In 2009, Gleason and his wife were in the process of adopting a baby from Ethiopia named Kennedy. Before they could bring her home, however, she died — the result, Gleason said, of a seemingly preventable combination of malnutrition and diarrhea.
“This loss redirected my academic teaching, research, and service activities at Georgia Tech,” said Gleason. “Since then, I’ve spent most of my career focused on developing resource-appropriate biomedical devices to reduce maternal and child mortality.”
“When we started this latest study, Ethiopian parents were reluctant to participate. But once we recruited a few mothers in the neonatal intensive care unit (NICU), everyone in the NICU community wanted their child to participate in our wearable health monitoring system.”
According to Yeo, “We designed the wearable patch as a safe, clinical-grade solution with minimal skin irritation. Its key design advantage lies in the use of nanomembranes, which allows the device to be soft and highly conformal to the baby's skin. Wearing the device helps to ensure critical events are not missed since the built-in automation acts as a force multiplier, freeing clinical staff to focus more on complex decision-making rather than manual data acquisition.”
“Rudy has a deep love for the people of Ethiopia. I feel fortunate to have met him as we embark on this project aimed at helping sick babies in the country. Without his support, I could not envision bringing this technology to Ethiopia,” said Yeo.
During the past decade, child mortality rates have decreased in Ethiopia, but newborn deaths have remained mostly unchanged. Both Yeo and Gleason feel their new wearable neonatal device could significantly lower mortality rates for newborns in Ethiopia as they advance this research.
Citation: Zhou, L., Joseph, M., Lee, Y.J. et al. Soft, all-in-one, nanomembrane wearable system for advancing neonatal health monitoring in Ethiopia. npj Digit. Med. 8, 575 (2025).
DOI: https://doi.org/10.1038/s41746-025-01974-8
Funding: Gates Foundation (INV-006189) and the National Institutes of Health (R01HD100635). This work was also supported by the Imlay Foundation—Innovation Fund.
Wearable chest-mounted patch and forehead-mounted pulse oximeter shown close-up
Professor Rudy Gleason with baby and parents at a hospital in Ethiopia
Professors Hong Yeo and Rudy Gleason
Walter Rich
Research Communications
Generative AI Takes Center Stage at Georgia Tech’s 2025 Research Collaboration Forum
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Researchers and partners from Georgia Tech and HBCUs at the 2025 Research Collaboration Forum.
The Year in Photos — 2025
Jingle Bells, Empty Shelves: Inside the Toy Crunch
Dec 02, 2025 —
For generations, holiday toy production has followed a predictable rhythm — designs finalized in spring, manufacturing in summer, and shipments arriving just in time for December. This year, that rhythm has been thrown off balance. Global supply chain disruptions, steep tariffs, and soaring shipping costs have created a perfect storm for toy makers, forcing them to rethink strategies and timelines. The result: fewer choices, higher prices, and parents scrambling to secure gifts before shelves run bare.
Tariffs and Turbulence
Political shifts have turned the toy industry’s supply chain into a game of Operation. Stephen Chininis, professor of the practice at Georgia Tech and longtime toy designer, says the impact of tariffs is only beginning to hit consumers.
“Prices are going to go up; there’s no doubt about it, and some products will be scarce,” Chininis explained. “This is not intentional scarcity sometimes built into the toy industry. This is accidental scarcity.”
Manufacturers once relied on China’s speed and low labor costs to react quickly to trends. Now, uncertainty around tariffs has companies freezing expansion and shifting production to places like Vietnam and Thailand, sometimes still under Chinese ownership. Add in skyrocketing shipping costs, and containers that once cost $2,500 now run $20,000.
Industry data confirms the pressure: China still produces nearly 80% of toys and 90% of holiday decorations sold in the U.S., and tariffs as high as 145% have frozen supply chains, causing widespread order cancellations and delays. Reports show 87% of midsize companies and 81% of small companies have delayed orders, and nearly half warn they could shut down if costs persist.
Parents in Panic Mode
When Santa’s workshop slows down, parents speed up. Timothy Halloran, marketing lecturer at Georgia Tech, warns that shortages can spark buying frenzies.
“If people are aware of the toy shortage, a consumer buying panic may set in,” Halloran said. “If it’s a popular toy, you might see a black market emerge — think eBay — where some people are willing to pay top dollar.”
Halloran predicts early shopping and alternative gifts will become the norm. “Those ‘in the know’ will buy early. Those that miss out will either purchase through the black market or resort to alternatives,” he said.
This year, that advice matters more than ever. Analysts report toy prices rose 2.2% between April and May, the steepest monthly increase in four years, and some items could cost two to three times more by Christmas. Retailers are keeping inventories lean, which means fewer choices and faster sellouts for trending toys. Toy manufacturers warn that holiday assortments will be smaller, with fewer backup units behind shelves.
What’s Next for Santa’s Supply Chain
Despite the chaos, Chininis sees the opportunity in innovation. “There’s a big resurgence in non-technology-based toys,” he said. “Parents don’t want extra screens, so designers are finding ways to teach and entertain without relying on electronics. It’s definitely a design-thinking exercise, and some really good toys have come out of that.”
Sustainability is also trending. The eco-friendly toy market is projected to grow from $12.5 billion in 2024 to $23.1 billion by 2033, driven by demand for biodegradable materials and recyclable packaging. According to The Toy Association, 45% of parents under 40 consider a toy’s environmental impact when purchasing, and 55% of parents prefer toys that are sustainable or eco-friendly. Major brands like Mattel and Playmobil are pledging to use 100% recycled or bio-based plastics by 2030, signaling a long-term shift toward greener play.
For parents, the best advice is to shop early, stay flexible, and remember that sometimes the simplest gifts like a kite, a ball, or a board game bring the most joy.
Georgia Tech Researchers Among World’s Most Highly Cited in 2025
Dec 02, 2025 —
Georgia Tech proudly announces its faculty who have been named to the Clarivate Highly Cited Researchers 2025 list. This list is a global recognition of scholars with work among the top 1% most cited within their fields. This distinction demonstrates Georgia Tech’s leadership in advancing research with broad and lasting impact.
The Institute’s highly cited researchers include:
- Ian F. Akyildiz - retired professor, Electrical and Computer Engineering
- Antonio Facchetti – professor, Hightower Chair, Materials Science and Engineering
- Maohong Fan – adjunct professor, Civil and Environmental Engineering
- Konstantinos Konstantinidis – professor, Environmental Engineering
- Nian Liu – associate professor and Robert G. Miller Faculty Fellow, Chemical and Biomolecular Engineering
- Anant Madabhushi – professor, Biomedical Engineering
- H. Jerry Qi – Woodruff Professor, Mechanical Engineering
- Rampi Ramprasad – Regents’ Entrepreneur, Materials Science and Engineering
- Rodney J. Weber – professor, Earth and Atmospheric Sciences
- C.P. Wong – Charles Smithgall Institute Endowed Chair and Regents’ Professor, Materials Science and Engineering
“Our faculty’s recognition among the world’s most highly cited demonstrates Georgia Tech’s commitment to pioneering discoveries and solving complex global challenges through research,” said Tim Lieuwen, executive vice president for Research. “Congratulations to each of them on this impressive achievement.”
Clarivate’s annual list identifies researchers whose published work demonstrates exceptional influence, based on citation data from the Web of Science Core Collection over the past 11 years. These scholars have authored multiple Highly Cited Papers, which are publications consistently ranked in the top 1% by citations in their respective fields.
Manufacturing’s Future Is High Tech
Dec 02, 2025 —
For decades, manufacturing has been synonymous with job creation, a pillar of economic growth and stability. Today, the industry is evolving into something far more dynamic: a hub for innovation, sustainability, and purpose-driven careers. Experts say this transformation is reshaping not only what manufacturing looks like but why it matters.
Beyond the Assembly Line: A High-Tech Reality
“People still picture manufacturing as the assembly lines of the early 20th century,” says Thomas Kurfess, executive director of the Georgia Tech Manufacturing Institute. “The reality is very different. Modern plants are among the most advanced environments you’ll find, packed with robotics, automation, and data-driven systems. In fact, if you want to see the largest number of robots in one location, it will be at an automotive assembly plant.”
That disconnect between perception and reality is one reason manufacturers struggle to fill roles despite record demand. Kurfess notes that students often overlook manufacturing careers because they assume the work is low tech. “We need to expose educators, parents, and students to what manufacturing truly looks like,” he says. Facility tours and partnerships with technical colleges can help shift the narrative.
Pinar Keskinocak, H. Milton and Carolyn J. Stewart School Chair in the School of Industrial and Systems Engineering, agrees: “Showcasing innovations like AI-driven automation, 3D printing, and smart factories is key to changing perceptions.”
Green Tech and Digital Transformation
The rise of electric vehicles, batteries, and renewable energy is accelerating this shift. “Green technology presents a transformative opportunity for U.S. manufacturing,” Kurfess explains. “It is not just about sustainability; it is about national security and global competitiveness.”
These sectors are inherently digital, says Nagi Gebraeel, Georgia Power Term Professor in the College of Engineering. “Green tech manufacturing is being built in an era when advanced digital technologies are mature and widely accessible. Factories are designed from the ground up with automation and sensing embedded, creating highly interconnected systems.”
This evolution demands new skills. The labor force must navigate environments where operational technology and information technology converge. Gebraeel predicts that by 2035, manufacturing leaders will increasingly come from operations and data-driven backgrounds rather than traditional IT.
The Workforce Challenge
Despite the promise of high-tech careers, talent pipelines remain thin. Manpreet Hora, senior associate dean in the Scheller College of Business, points to a “demand-supply mismatch” driven by rapidly changing skill requirements. “Manufacturing now needs workers who combine technical, digital, and soft skills,” he says. “Meanwhile, younger workers often gravitate toward service industries for perceived growth and tech exposure. The manufacturing sector will collectively need to reposition themselves as employers of choice by making their digital tools visible, highlighting career progression, and offering flexible learning pathways.”
Experts agree that education must adapt. Kurfess advocates for a systemwide approach starting in elementary school, while Gebraeel emphasizes integrating AI into curricula and offering modular micro-credentials for upskilling. Hora adds that hands-on training should reflect realities like AI-enabled operations and sustainability-focused processes.
Purpose and Innovation
For younger professionals seeking meaningful work, manufacturing offers more than a paycheck. “These are high-tech, high-impact roles where workers build products that move the world, from aircraft and medical devices to renewable energy systems,” Kurfess says.
To position the industry as an innovation hub, leaders must embrace technologies that enhance efficiency and quality while fostering collaboration across schools, businesses, and government. “Modernizing the image of manufacturing demands aligned messaging and shared investment,” he adds.
Looking Ahead
By 2035, experts envision a workforce fluent in AI, committed to lifelong learning, and working in environments where cyber and physical systems are seamlessly integrated. Manufacturing will remain a cornerstone of economic strength, but its true value will lie in its ability to innovate, adapt, and deliver purpose-driven careers.
Ayana Isles
Senior Media Relations Representative
Institute Communications
IMS Launches Series on Interdisciplinary Innovation with AI Computing Panel
Dec 01, 2025 —
The Institute for Matter and Systems (IMS) hosted the inaugural Boundaries and Breakthroughs panel on Nov. 11, setting the stage for a new era of interdisciplinary dialogue at Georgia Tech. The event, held in the Marcus Nanotechnology building, brought together experts in electrical engineering, computer architecture, and computer systems design to tackle one of today’s pressing challenges: artificial intelligence (AI) scalability and sustainable high-performance computing.
As one of Georgia Tech’s 11 interdisciplinary research institutes, IMS is designed to break down silos between traditional academic units. By operating core user facilities and fostering collaborative research, IMS creates a unique ecosystem where device-level innovation meets systems-level design. This event personified that mission by connecting researchers who typically work on different ends of the stack.
“We’re looking for opportunities to bring people together to have discussions that are both informative and potentially create a little bit of friction in the best possible way around trending topics in science and engineering,” said Mike Filler, IMS deputy director, during opening remarks.
The panel was moderated by Divya Mahajan, assistant professor in the School of Electrical and Computer Engineering, and featured Moinuddin Qureshi, professor of computer science; Anand Iyer, assistant professor of computer science; and Asif Khan, associate professor in electrical and computer engineering.
The discussion explored the dynamics between compute abundance and energy constraints. As AI models scale up, power consumption has become a societal issue, driving up energy demands and even influencing political conversations. The panelists agreed that the bottleneck isn’t compute — a computer’s ability to process and execute tasks — but data movement. Moving data uses 100 to 1,000 times more energy than computation, making memory systems the critical frontier.
The conversation highlighted how breakthroughs in compute must occur at every layer — from individual devices to full computer systems. At the device level, Khan mentioned emerging memory technologies and “beyond CMOS” approaches such as embedding compute within memory and exploring bio-inspired architectures.
From a computer architecture level, Qureshi advocated rethinking interfaces and creating designs optimized for the future of computing. AI needs regular patterns to work optimally, and current patterns are not set up for that.
“If you want efficiency, design systems that make sense for AI,” Qureshi said. “Develop new interfaces, develop new modules, architectures, and organization that make for a specific pattern.”
At the systems level, Iyer stressed practical strategies like near-memory compute and energy-aware scheduling while acknowledging the need for co-design between hardware and software.
“Now in terms of brains or bio-inspired computing, my conjecture is that there is currently no hardware that is capable of doing it,” Khan said. He also noted that right now, there is no computer or algorithm that has the scale of computing comparable to human brain power.
The panelists didn’t shy away from provocative ideas — such as whether graphic processing units are the final solution for AI and whether matrix multiplication alone can lead to artificial general intelligence. While opinions varied, all agreed that organizations like IMS are key to bringing together diverse expertise to tackle these questions collaboratively.
The Boundaries and Breakthroughs series continues in January with a panel on bioelectronics and medical technologies, reinforcing IMS’s commitment to fostering dialogue that spans the full spectrum of innovation.
Amelia Neumeister | Research Communications Program Manager
The Institute for Matter and Systems
Record-Breaking Simulation Boosts Rocket Science and Supercomputing to New Limits
Dec 01, 2025 —
Spaceflight is becoming safer, more frequent, and more sustainable thanks to the largest computational fluid flow simulation ever ran on Earth.
Inspired by SpaceX’s Super Heavy booster, a team led by Georgia Tech’s Spencer Bryngelson and New York University’s Florian Schäfer modeled the turbulent interactions of a 33-engine rocket. Their experiment set new records, running the largest ever fluid dynamics simulation by a factor of 20 and the fastest by over a factor of four.
The team ran its custom software on the world’s two fastest supercomputers, as well as the eighth fastest, to construct such a massive model.
Applications from the simulation reach beyond rocket science. The same computing methods can model fluid mechanics in aerospace, medicine, energy, and other fields. At the same time, the work advances understanding of the current limits and future potential of computing.
The team finished as runners-up for the 2025 Gordon Bell Prize for its impactful, multi-domain research. Referred to as the Nobel Prize of supercomputing, the award was presented at the world’s top conference for high-performance computing (HPC) research.
“Fluid dynamics problems of this style, with shocks, turbulence, different interacting fluids, and so on, are a scientific mainstay that marshals our largest supercomputers,” said Bryngelson, an assistant professor with the School of Computational Science and Engineering (CSE).
“Larger and faster simulations that enable solutions to long-standing scientific problems, like the rocket propulsion problem, are always needed. With our work, perhaps we took a big dent out of that issue.”
The Super Heavy booster reflects the space industry’s move toward reusable multi-engine first-stage rockets that are easier to transport and more economical overall.
However, this shift creates research and testing challenges for new designs.
Each of Super Heavy’s 33 thrusters expels propellant at ten times the speed of sound. As individual engines reach extreme temperatures, pressures, and densities, their combined interactions with the airframe make such violent physics even more unpredictable.
Frequent physical experiments would be expensive and risky, so scientists rely on computer models to supplement the engineering process.
Bryngelson’s flagship Multicomponent Flow Code (MFC) software anchored the experiment. MFC is an open-source computer program that simulates fluid dynamic models. Bryngelson’s lab has been modifying MFC since 2022 to run on more powerful computers and solve larger problems.
In computing terms, this MFC-enhanced model simulated fluid flow resolution at 200 trillion grid points and one quadrillion degrees of freedom. These metrics exceeded previous record-setting benchmarks that tallied 10 trillion and 30 trillion grid points.
This means MFC simulations provide greater detail and capture smaller-scale features than previous approaches. The rocket simulation also ran four times faster and achieved 5.7 times the energy efficiency of comparable methods.
Integrating information geometric regularization (IGR) into MFC played a key role in attaining these results. This new approach improved the simulation’s computational efficiency and overcame the challenge of shock dynamics.
In fluid mechanics, shock waves occur when objects move faster than the speed of sound. Along with hampering the performance of airframes and propulsion systems, shocks have historically been difficult to simulate.
Computational scientists have used empirical models based on artificial viscosity to account for shocks. Although these approaches mimic the physical effects of shock waves at the microscopic scale, they struggle to effectively capture the large-scale features of the flow.
Information geometry uses curved spaces to study concepts of statistics and information. IGR uses these tools to modify the underlying geometry in fluid dynamics equations. When traveling in the modified geometry, fluid in the model preserves the shocks in a more natural way.
“When regularizing shocks to much larger scales relevant in these numerical simulations, conventional methods smear out important fine-scale details,” said Schäfer, an assistant professor at NYU’s Courant Institute of Mathematical Sciences.
“IGR introduces ideas from abstract math to CFD that allow creating modified paths that approach the singularity without ever reaching it. In the resulting fluid flow, shocks never become too spiky in simulations, but the fine-scale details do not smear out either.”
Simulating a model this large required the Georgia Tech researchers to run MFC on El Capitan and Frontier, the world's two fastest supercomputers.
The systems are two of four exascale machines in existence. This means they can solve at least one quintillion (“1” followed by 18 zeros) calculations per second. If a person completed a simple math calculation every second, it would take that person about 30 billion years to reach one quintillion operations.
Frontier is housed at Oak Ridge National Laboratory and debuted as the world’s first exascale supercomputer in 2022. El Capitan surpassed Frontier when Lawrence Livermore National Laboratory launched it in 2024.
To prepare MFC for performance on these machines, Bryngelson’s lab followed a methodical approach spanning years of hardware acquisition and software engineering.
In 2022, Bryngelson attained an AMD MI210 GPU accelerator. Optimizing MFC on the component played a critical step toward preparing the software for exascale machines.
AMD hardware underpins both El Capitan and Frontier. The MI300A GPU powers El Capitan while Frontier uses the MI250X GPU.
After configuring MFC on the MI210 GPU, Bryngelson’s lab ran the software on Frontier for the first time during a 2023 hackathon. This confirmed the code was ready for full-scale deployment on exascale supercomputers based on AMD hardware.
In addition to El Capitan and Frontier, the simulation ran on Alps, the world’s eight-fastest supercomputer based at the Swiss National Supercomputing Centre. It is the largest available system that features the NVIDIA GH200 Grace Hopper Superchip.
Like with AMD GPUs, Bryngelson acquired four GH200s in 2024 and began configuring MFC to the latest hardware innovation powering New Age supercomputers. Later that year, the Jülich Research Centre accepted Bryngelson’s group into an early access program to test JUPITER, a developing supercomputer based on the NVIDIA superchip.
The group earned a certificate for scaling efficiency and node performance on the way toward validating that their code worked on the GH200. The early access project proved successful for JUPITER, which launched in 2025 as Europe’s fastest supercomputer and fourth fastest in the world.
“Getting the level of hands-on experience with world-leading supercomputers and computing resources at Georgia Tech through this project has been a fantastic opportunity for a grad student,” said CSE Ph.D. student Ben Wilfong.
“To leverage these machines, I learned more advanced programming techniques that I’m glad to have in my tool belt for future projects. I also enjoyed the opportunity to work closely with and learn from industry experts from NVIDIA, AMD, and HPE/Cray.”
El Capitan, Frontier, JUPITER, and Alps maintained their rankings at the 2025 International Conference for High Performance Computing Networking, Storage and Analysis (SC25). Of note, the TOP500 announced at SC25 that JUPITER surpassed the exaflop threshold.
The SC Conference Series is one of two venues where the TOP500 announces updated supercomputer rankings every June and November. The TOP500 ranks and details the 500 most powerful supercomputers in the world.
The SC Conference Series serves as the venue where the Association for Computing Machinery (ACM) presents the Gordon Bell Prize. The annual award recognizes achievement in HPC research and application. The Tech-led team was among eight finalists for this year’s award.
Along with Bryngelson, Georgia Tech members included Ph.D. students Anand Radhakrishnan and Wilfong, postdoctoral researcher Daniel Vickers, alumnus Henry Le Berre (CS 2025), and undergraduate student Tanush Prathi.
Schäfer’s partnership with the group stems from his previous role as an assistant professor at Georgia Tech from 2021 to 2025.
Collaborators on the project included Nikolaos Tselepidis and Benedikt Dorschner from NVIDIA, Reuben Budiardja from ORNL, Brian Cornille from AMD, and Stephen Abbot from HPE. All were co-authors of the paper and named finalists for the Gordon Bell Prize.
“I’m elated that we have been nominated for such a prestigious award. It wouldn't have been possible without the combined and diligent efforts of our team,” Radhakrishnan said.
“I’m looking forward to presenting our work at SC25 and connecting with other researchers and fellow finalists while showcasing seminal work in the field of computing.”
Bryant Wine, Communications Officer
bryant.wine@cc.gatech.edu
Clean, Old-Fashioned Collaboration: Engineering the Future of Healthcare at Georgia Tech and UGA
Nov 24, 2025 —
Tim Lieuwen and Chris King (Credit: Rob Felt)
If you’ve lived in Georgia long enough, you’ve almost certainly heard the friendly jabs tossed across divided Thanksgiving tables. On one side, a smirk and a mention of the “North Avenue Trade School.” On the other, a pointed retort: “To hell with Georgia.”
Few rivalries run deeper than the one known as “Clean, Old-Fashioned Hate,” the annual showdown between Georgia Tech and the University of Georgia (UGA). On Friday afternoon, November 28, the two will face off in one of the most anticipated matchups in years. These teams don’t like each other, and for a few hours every year, neither do friends, families, and even significant others.
Off the field, however, the schools are proving that collaboration, not competition, is the schools’ true strength.
For more than a century, Georgia’s flagship universities have united around complementary strengths, tackling the state’s biggest challenges together. That starts with making Georgians healthier.
“When Georgia Tech and UGA combine their strengths, together we create solutions that neither institution could achieve alone,” said Tim Lieuwen, executive vice president for Research at Georgia Tech. “These collaborations accelerate innovation in healthcare, improve lives across our state, and demonstrate that partnership — not rivalry — is Georgia’s most powerful tradition."
“The common denominator between these two great institutions is the populations they serve,” said Chris King, interim vice president for Research at UGA. “We have a duty to find solutions that help improve the quality of life for all Georgians, and that’s what these partnerships are all about.”
From programs like the Georgia Clinical and Translational Science Alliance (Georgia CTSA) to the National Science Foundation’s Engineering Research Center for Cell Manufacturing Technologies (CMaT), researchers at UGA and Georgia Tech are setting rivalries aside to build lasting partnerships that fuel innovation and expand the workforce to meet the state’s needs.
Pushing Cell Therapy Across the Goal Line
CMaT is an NSF-funded consortium of more than seven universities and 40 member companies. At Georgia Tech and UGA, teams are conducting many early stage translational projects to improve manufacturing of cell-based therapeutics.
One joint project between Andrés García, executive director of Georgia Tech’s Parker H. Petit Institute for Bioengineering & Bioscience, and John Peroni, the Dr. Steeve Giguere Memorial Professor in Large Animal Medicine in UGA’s College of Veterinary Medicine, addresses treatment of bacterial infections that can follow bone repair surgeries.
Bone fractures and non-union defects often require surgical implants, but 1-5% are compromised by bacterial infection, costing hospitals more than $1.9 billion annually. Current treatments are limited to sustained, high doses of antibiotics, which are less effective and can generate antibiotic-resistant bacteria. García and Peroni are engineering synthetic biomaterials that locally deliver antimicrobial agents to eliminate infections and promote bone repair.
Steven Stice, D.W. Brooks Distinguished Professor and Georgia Research Alliance Eminent Scholar at UGA’s Regenerative Bioscience Center, is also working with Georgia Tech’s Andrei Fedorov, professor and Rae S. and Frank H. Neely Chair in the George W. Woodruff School of Mechanical Engineering, to improve the quality and control of producing natural, cell-derived healing materials for regenerative medicine.
Adult cells secrete tiny, bubble-like vesicles that help other cells heal and regenerate tissue. Stice developed methods to boost vesicle production, while Fedorov created a probe that accelerates the process.
“Cells simply don’t secrete these healing vesicles in the quantities needed for scalable, clinical-grade treatments,” said Stice, UGA lead and co-principal investigator for CMaT. “Our collaborative work changes that, accelerating production in a way that finally makes large-scale regenerative therapies feasible.”
“Georgia Tech and UGA's collective commitment to advancing science and technology exceeds the intensity of our athletic rivalry,” Fedorov said. “Together, we’re advancing cell and therapy biomanufacturing to develop lifesaving treatments for the most devastating diseases.”
Georgia Tech’s Francisco Robles and UGA’s Lohitash Karumbaiah are using manufactured T cells to target cancer. Robles, who leads the Optical Imaging and Spectroscopy Lab in the Wallace H. Coulter Department of Biomedical Engineering, developed quantitative Oblique Back-illumination Microscopy (qOBM) to monitor tumor growth in real time. The method allows scientists to visualize patient-derived glioblastoma cell clusters generated in the Karumbaiah Lab, tracking tumor structure and behavior at various stages.
“Assessing therapeutic potency is often complex, costly, and ineffective for solid tumors,” Karumbaiah said. “qOBM simplifies the process by providing real-time, label-free monitoring of therapeutic efficacy against 3D solid tumors.”
The work could help doctors personalize cancer treatments by providing early, detailed signs of whether a therapy is working.
“This technique is more compact and affordable and lets us watch T cells attack cell cultures in real time,” Robles said. “This breakthrough could transform how we study disease and screen new treatments.”
A Playbook for Local Healthcare
Created in 2007 by the National Institutes of Health, Georgia CTSA is one of several NIH-funded national partnerships advancing new health therapeutics and practices. Since 2017, it has comprised UGA, Georgia Tech, Emory, and the Morehouse School of Medicine. The alliance’s reach extends far beyond campus borders, bringing together researchers, clinicians, professional societies, and community and industry partners to identify local health challenges and translate research into practical solutions.
And out of this alliance have come many collaborative studies among CTSA’s members.
One, the Georgia Health Landscape Dashboard, is a tool to identify local health gaps and connect regional health professionals or policymakers with the researchers who can best address their community’s challenges. UGA College of Family and Consumer Sciences Associate Professors Alison Berg and Dee Warmath, along with community health engagement coordinator Courtney Still Brown, are working with Georgia Tech’s Jon Duke, director of the Center for Health Analytics and Informatics at the Georgia Tech Research Institute and a principal research scientist in the School of Interactive Computing.
The dashboard has already helped match researchers with communities by combining epidemiological data with “community voice” insights through surveys of residents and local leaders.
For example, when examining diabetes data, the dashboard indicates Randolph County has the state’s highest prevalence, despite declining by about 8% between 2021-24. Meanwhile, Treutlen County’s rate increased 29.2% during the same period. Perhaps Treutlen’s need for diabetic care is a growing concern, while Randolph’s is being addressed. And perhaps Hancock County, which ranks diabetes its top priority in the community voice category, is in search of immediate solutions.
“The Landscape Dashboard is a fantastic example of how the unique expertise found at Georgia Tech and UGA can be brought together to create something truly valuable for all Georgia,” Duke said. “By bringing together a range of data sources and health analytics approaches, this collaboration has created a tool that delivers novel insights into health, community, and policy across the state.”
Supported by UGA Cooperative Extension and the Biomedical and Translational Sciences Institute, the project leverages a network of agents in every county across the state. Warmath said the project’s strength lies in its ability to connect research with real-world needs.
“To build a community-responsive ecosystem for biomedical research, scientists must recognize local needs, share progress with communities to foster trust and acceptance, recruit clinicians and industry partners, and strengthen the relationships between patient and caregiver,” Warmath said.
Teaming Up for Maternal Health
Warmath and a team of researchers at UGA, Georgia Tech, and Emory are also collaborating on an NIH-funded project uniting experts in maternal health, biostatistics, and consumer science to explore how wearable technologies could improve delivery-room care.
During childbirth, clinicians monitor countless maternal and fetal vitals — contractions, heart rates, oxygen levels, kidney function, and more. What new insights, the researchers asked, could advanced wearable technologies offer in the delivery room, and what barriers might prevent their use?
Using nationwide surveys and focus groups, the team gathered information from a representative sample of pregnant, postpartum, and reproductive-age women, as well as healthcare professionals, to examine acceptance of wearable health technologies during labor and delivery. In their analysis of this rich data source, the team is identifying key variables that reveal gaps in technology acceptance and the unique needs of diverse maternal populations.
Each partner institution brings unique expertise. At Emory, principal investigator Suchitra Chandrasekaran contributes clinical insights from direct patient care. At UGA, Warmath applies her knowledge in consumer science to analyze end-user motivation, attitudes, and behaviors. At Georgia Tech, experts like Sarah Farmer in the Center for Advanced Communications Policy’s Home Lab facilitate large-scale data collection.
With data collection now complete, the team is analyzing results to inform future design and deployment of wearable technologies.
“Each school has a different perspective,” Farmer said. “It’s not as simple as one school does this but doesn’t do that. Each has their expertise, but they offer different perspectives and different resources that, when pooled, can make our research that much more effective.”
Whether advancing maternal health, mapping Georgia’s health needs, or engineering next-generation therapies, UGA and Georgia Tech continue to prove that collaboration is Georgia’s strongest tradition. Further, the undergraduate and graduate students who work in these labs and others represent the state’s highly skilled workforce of tomorrow.
“When our institutions work together, Georgia wins,” Warmath said.
— By David Mitchell
Andrés J. García
John Peroni
The Dynamic Mass Spectrometry Probe developed to monitor the health of living cell cultures (photo credit: Rob Felt)
Sarah Farmer
For media inquiries:
Angela Bajaras Prendiville
Director of Media Relations
media@gatech.edu