Yonggang Ke

Yonggang Ke's research is highly interdisciplinary combining chemistry, biology, physics, material science, and engineering. The overall mission of his research is to use interdisciplinary research tools to program nucleic-acid-based "beautiful structures and smart devices" at nanoscale, and use them for scientific exploration and technological applications. Specifically, his team focuses on (1) developing new DNA self-assembly paradigms for constructing DNA nanostructures with greater structural complexity, and with controllable sizes and shapes; (2) developing new imaging or drug delivery systems based on DNA nanostructuresl; (3) exploring design of novel DNA-based nanodevices for understanding basic biological questions at molecular level; (4) developing DNA-templated protein devices for constructing artificial bio-reactors.

For cancer-related research/application, Ke will focus on using DNA/RNA nanostructures as drug delivery vehicles. He is also interested in using DNA/RNA nanostructures to study cancer cell biology at molecular level.