Machelle Pardue

Machelle Pardue

Research Career Scientist, Center for Visual and Neurocognitive Rehabilitation

Dr. Pardue is a Research Career Scientist at the Atlanta VA Medical Center, and a Professor in Wallace H. Coulter Department of Biomedical Engineering at Georgia Institute of Technology and Emory University School of Medicine. Dr. Pardue received her B.S. in zoology from the University of Wyoming and her doctorate in vision science and biology at the University of Waterloo. Her post-doctorate training in visual electrophysiology was completed with Dr. Neal Peachey at Loyola School of Medicine and Hines VA Hospital in Chicago and focused on biocompatibility of retinal prosthetics. Dr. Pardue moved to Atlanta in 2000 to join the Atlanta VA Medical Center and Emory University Department of Ophthalmology. She moved her academic appointment to Biomedical Engineering in 2015. Her research interests are focused on developing treatments for people with vision loss. To this end, she has developed three research themes within her lab: 1) neuroprotective and restorative treatments for retinal degeneration, 2) early detection and treatment of diabetic retinopathy, and 3) retinal mechanisms of refractive development and myopia. Her research has been continuously supported by the Department of Veterans Affairs, NIH, and private companies (1999-present). She has served on several VA and NIH grant review panels and frequently reviews manuscripts for several journals including Journal of Neuroscience, Investigative Ophthalmology and Visual Sciences, Molecular Vision, Vision Research, Journal of Neuroscience Methods, Journal of Neurochemistry and PlosOne.


Office Location:
UAW 4104


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    Georgia Institute of Technology

    Wallace H. Coulter Department of Biomedical Engineering
    Research Focus Areas:
  • Neuroscience
  • Regenerative Medicine
  • Additional Research:
    Pardue's lab is focused on developing treatments for people with vision loss. Steps to successful treatment require understanding the mechanisms of the disease and characterizing temporal changes to identify therapeutic windows, with the ultimate goal of rehabilitation of visual function. She uses behavioral electrophysiological, morphological, molecular, and imaging approaches to evaluate changes in retinal function and structure. Her research is guided by applying knowledge of retinal circuits and visual processing, often leading to studies of cognition and the interaction of retinal and visual circuits during health and disease. Her studies start in animal models and move to human trials when possible.

    Research Affiliations: Regenerative Engineering and Medicine (REM), Integrated Cancer Research Center, Immunoengineering

    IRI Connection: