Levi Wood

Our research focuses on applying systems analysis approaches and engineering tools to identify novel clinical therapeutic targets for complex diseases. It is challenging to develop new treatments for these diseases, such as Alzheimer's disease(AD) and Traumatic Brain Injury (TBI), because they do not have a single genetic cause and they simultaneously present broad physiologic changes. By combining novel engineeredin vitroplatforms, mouse models, and multivariate computational systems analysis, we will be able to 1) capture a holistic systems-level understanding of complex diseases, and 2) isolate specific mechanisms driving disease. The ultimate goal of our laboratory is to use these tools to identify new mechanisms driving disease onset and progression that will translate to effective therapeutic strategies.

• Parker H. Petit Institute for Bioengineering and Bioscience